CD45 / LCA

protein tyrosine phosphatase, receptor type, C

CD45 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported.

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Products

Proteins (18)

Type

Over-Expression Lysate (2)

Recombinant (16)

Target

CD45 / LCA (18)

Publications

No (18)

Tag

6His, C-terminus (2)

6His-SUMO, N-terminus (1)

DDK (Flag)-His, C-terminus (1)

Fc (2)

GST, N-terminus (2)

His (3)

His-GST (1)

His-S (2)

Mouse IgG2a Fc, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (11)

Mouse (6)

Source

293T Cells (1)

Baculovirus (1)

E. coli (5)

HEK 293 Cells (3)

Human (2)

Human Cells (2)

Insect Cells (1)

Wheat Germ Extract (2)

Yeast (1)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (7)

Biologically Active

Biologically active (1)

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Human CD45 / LCA Protein (Recombinant His) (aa193-575) - LS-G13267

Source:

E. coli

Tag:

His

Molecular Weight:

45.1 kDa

Price:

10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723

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Human CD45 / LCA Protein (Recombinant Mouse IgG2a Fc, N-terminus) - LS-G134293

Source:

HEK 293 Cells

Tag:

Mouse IgG2a Fc, N-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 5.0 EU/mg protein (determined by LAL method).

Molecular Weight:

~65 kDa (SDS-PAGE)

Price:

50 µg/$442

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Human CD45 / LCA Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88597

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

147.1 kDa

Price:

20 µg/$215

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Mouse CD45 / LCA Protein (Recombinant 6His, C-terminus) - LS-G146286

Source:

Human

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

59.5 kDa

Price:

10 µg/$377; 50 µg/$795

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Human CD45 / LCA Protein (Recombinant DDK (Flag)-His, C-terminus) - LS-G142167

Source:

HEK 293 Cells

Tag:

DDK (Flag)-His, C-terminus

Molecular Weight:

63 kDa

Price:

20 µg/$1,107

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Human CD45 / LCA Protein (Recombinant 6His, C-terminus) - LS-G146495

Source:

Human

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

52.1 kDa

Price:

10 µg/$317; 50 µg/$529

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Human CD45 / LCA Protein (Recombinant His) (aa24-575) - LS-G23094

Source:

Yeast

Tag:

His

Molecular Weight:

62.78 kD

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

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Human CD45 / LCA Protein (Recombinant GST, N-terminus) (aa1207-1304) - LS-G59825

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human CD45 / LCA Protein (Recombinant GST, N-terminus) (aa390-570) - LS-G59826

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human CD45 / LCA Protein (Recombinant 6His-SUMO, N-terminus) (aa24-575) - LS-G56474

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Mouse CD45 / LCA Protein (Recombinant Fc) (Met1-Lys425) - LS-G98244

Source:

Human Cells

Tag:

Fc

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

71.7 kDa

Price:

100 µg/$721

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CD45 / LCA Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99886

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

147.1 kDa

Price:

100 µg/$710

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Human CD45 / LCA Protein (Recombinant His) - LS-G2802

Source:

E. coli

Tag:

His

Price:

20 µg/$361; 100 µg/$739; 4 µg/$261

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Human CD45 / LCA Protein (Recombinant Fc) (Met1-Lys414) - LS-G98035

Source:

Human Cells

Tag:

Fc

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

71.1 kDa

Price:

100 µg/$721

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Mouse CD45 / LCA Protein (Recombinant His-GST) (Arg453-Ser1152) - LS-G98243

Source:

Baculovirus

Tag:

His-GST

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

108.2 kDa

Price:

100 µg/$1,120

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Mouse CD45 / LCA Protein (Recombinant) (Arg453-Ser1152) - LS-G138352

Source:

Insect Cells

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

81 kDa

Price:

100 µg/$1,120

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Mouse CD45 / LCA Protein (Recombinant His-S) (aa371-556) - LS-G13263

Source:

E. coli

Tag:

His-S

Molecular Weight:

26.6 kDa

Price:

10 µg/$268; 50 µg/$362; 100 µg/$577; 200 µg/$722; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,708; 2 mg/$1,934

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Mouse CD45 / LCA Protein (Recombinant His-S) (aa644-900) - LS-G13276

Source:

E. coli

Tag:

His-S

Molecular Weight:

35.4 kDa

Price:

10 µg/$268; 50 µg/$362; 100 µg/$577; 200 µg/$722; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,708; 2 mg/$1,934

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