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CD40L

CD40 ligand

TNFSF5 is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in inability of immunoglobulin class switch and is associated with hyper IgM syndrome.

Gene Name: CD40 ligand
Family/Subfamily: TNF , not assigned-TNF
Synonyms: CD40LG, CD154, CD154 antigen, CD40-L, CD40 ligand, CD40L, gp39, HIGM1, IGM, IMD3, T-BAM, TNFSF5, CD40 antigen ligand, CD54, HCD40L, T-B cell-activating molecule, T-cell antigen Gp39, TNF-related activation protein
Target Sequences: NM_000074 NP_000065.1 P29965

☰ Filters
Products
Proteins (47)
Over-Expression Lysate (2)
Recombinant (45)
CD40L (47)
Bind (3)
ELISA (3)
Func (3)
SDS-PAGE (3)
Animal-free (1)
No (47)
6His, N-terminus (5)
6His-AVI, N-terminus (1)
DDK (Flag)-Human ACRP30headless aa 18-111 (3)
GST (2)
GST, N-terminus (1)
His (2)
His, N-Terminal (2)
His,C-terminus (2)
His,N-terminus (2)
His-GST (5)
His-S (2)
Human IgG1 Fc (1)
Human IgG1 Fc, N-terminus (2)
Mouse IgG1 Fc, N-terminus (1)
Myc-DDK (Flag) (2)
Bovine (1)
Human (30)
Mouse (6)
Pig (3)
Rabbit (2)
Rat (2)
Rhesus monkey (2)
293T Cells (1)
CHO Cells (4)
E. coli (26)
HEK 293 Cells (4)
Human (2)
Human Cells (1)
Mammalian Cells (4)
Wheat Germ Extract (2)
Yeast (2)
Purified (10)
Low endotoxin level (23)
Biologically active (13)
Animal-free (1)
CD40L Protein - Recombinant Cluster Of Differentiation 40 Ligand By SDS-PAGE
Select
E. coli
His, N-Terminal
14.4 kDa
10 µg/$307; 50 µg/$602; 100 µg/$962; 200 µg/$1,156; 1 mg/$2,369; 500 µg/$1,876; 5 mg/$4,201; 2 mg/$2,562
Select
E. coli
6His, N-terminus
20.3 kD
1 mg/$1,679; 100 µg/$598; 20 µg/$405
Select
Yeast
6His, N-terminus
18.2 kD
100 µg/$679; 20 µg/$429; 1 mg/$1,973
CD40L Protein
Select
E. coli
His
17.7 kDa
10 µg/$297; 50 µg/$542; 100 µg/$865; 200 µg/$1,065; 1 mg/$2,239; 500 µg/$1,755; 5 mg/$3,781; 2 mg/$2,430
CD40L Protein - Recombinant Cluster Of Differentiation 40 Ligand By SDS-PAGE
Select
E. coli
His-GST
43.3 kDa
10 µg/$297; 50 µg/$542; 100 µg/$865; 200 µg/$1,065; 1 mg/$2,239; 500 µg/$1,755; 5 mg/$3,781; 2 mg/$2,430
CD40L Protein
Select
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
~16 kDa
50 µg/$291; 250 µg/$494; 1 mg/$1,401
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
16.3 kDa
10 µg/$268; 50 µg/$349
Select
CHO Cells
DDK (Flag)-Human ACRP30headless aa 18-111
Less than 0.02 EU/µg protein (determined by LAL method).
~35-40kDa
10 µg/$428
CD40L Protein - Measured by its binding ability in a functional ELISA. Immobilized human CD40 at 2 µg/ml (100 µl/well) can bind human CD40L Fc Chimera with a linear ranger of 1.28-32 ng/ml.
Select
HEK 293 Cells
Human IgG1 Fc, N-terminus
Bind ELISA Func SDS-PAGE
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant human CD40L/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 386 amino acids and has a predicted molecular mass of 42.8 kDa. The apparent molecular mass of rh CD40L/Fc monomer is approximately 45 kDa in SDS-PAGE under reducing conditions.
50 µg/$364; 500 µg/$1,285
CD40L Protein - Measured by its binding ability in a functional ELISA. Immobilized human CD40L at 10 µg/ml (100 µl/well) can bind human CD40 / Fc with a linear range of 7.8-125 ng/ml.
Select
E. coli
His,C-terminus
Bind ELISA Func SDS-PAGE
Biologically active
The recombinant human CD40L consists of 161 amino acids and has a calculated molecular mass of 17.7 kDa. It migrates as an 18 kDa band in SDS-PAGE under reducing conditions.
100 µg/$410; 1 mg/$2,261
CD40L Protein - Measured by its binding ability in a functional ELISA. Immobilized mouse CD40L-Fc at 10 µg/mL (100 µl/well) can bind biotinylated mouse CD40-Fch, The EC50 of biotinylated mouse CD40-Fch is 33-49 ng/mL.
Select
HEK 293 Cells
Human IgG1 Fc, N-terminus
Bind ELISA Func SDS-PAGE
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant mouse CD40LG/Fc is a disulfide-linked homodimer. The reduced monomer comprises 406 amino acids and has a calculated molecular mass of 44.4 kDa. The apparent molecular mass of the monomer is approximately 50 kDa in SDS-PAGE under reducing conditions.
50 µg/$364; 500 µg/$1,379
Select
E. coli
6His, N-terminus
1 mg/$1,679; 100 µg/$598; 20 µg/$405
CD40L Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CD40L Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Yeast
6His, N-terminus
100 µg/$446; 20 µg/$336; 1 mg/$1,460
Select
E. coli
His-S
17.7 kDa
10 µg/$297; 50 µg/$542; 100 µg/$865; 200 µg/$1,065; 1 mg/$2,239; 500 µg/$1,755; 5 mg/$3,781; 2 mg/$2,430
CD40L Protein - Recombinant Cluster Of Differentiation 40 Ligand By SDS-PAGE
Select
E. coli
His-GST
49.2 kDa
10 µg/$288; 50 µg/$487; 100 µg/$780; 200 µg/$972; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298
CD40L Protein - Recombinant Cluster Of Differentiation 40 Ligand By SDS-PAGE
Select
E. coli
His, N-Terminal
14.4 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
CD40L Protein - Recombinant Cluster Of Differentiation 40 Ligand By SDS-PAGE
Select
E. coli
His-GST
48.1 kDa
10 µg/$292; 50 µg/$512; 100 µg/$817; 200 µg/$1,018; 1 mg/$2,168; 500 µg/$1,690; 5 mg/$3,571; 2 mg/$2,359
CD40L Protein - Recombinant Cluster Of Differentiation 40 Ligand By SDS-PAGE
Select
E. coli
His-S
23.8 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
CD40L Protein - Recombinant Cluster Of Differentiation 40 Ligand By SDS-PAGE
Select
E. coli
His-GST
61.7 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
CD40L Protein - Recombinant Cluster Of Differentiation 40 Ligand By SDS-PAGE
Select
E. coli
His-GST
51.9 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
CD40L Protein
Select
E. coli
GST
51.2 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
CD40L Protein - 12.5% SDS-PAGE of human CD40LG stained with Coomassie Blue
Select
Wheat Germ Extract
GST
55.11 kDa
10 µg/$479; 25 µg/$670
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
16.2kD
10 µg/$248; 50 µg/$313; 500 µg/$743; 1 mg/$1,048
Select
Human Cells
None
Less than 1.0 EU/µg protein (determined by LAL method).
16.2kD
10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).