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CD3G

CD3g molecule, gamma (CD3-TCR complex)

CD3G is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency.

Gene Name: CD3g molecule, gamma (CD3-TCR complex)
Synonyms: CD3G, CD3-GAMMA, CD3g antigen, T-cell receptor gamma chain, T-cell receptors gamma chain, T3G, T-cell receptor T3 gamma chain
Target Sequences: NM_000073 NP_000064.1 P09693

Publications (1)

1
Intrapulmonary Delivery of CpG Microparticles Eliminates Lung Tumors. Sato T, Shimosato T, Ueda A, Ishigatsubo Y, Klinman DM. Molecular cancer therapeutics. 2015 14:2198-205. (ICC, Flo; Mouse, Human) [Full Text Article] [PubMed:26206336] [PMC:PMC4596766]

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
CD3G (5)
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6His, N-terminus (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (2)
Crab-eating macaque (1)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Yeast (1)
Purified (2)
CD3G Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
CD3G Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Yeast
6His, N-terminus
100 µg/$679; 20 µg/$429; 1 mg/$1,973
CD3G Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CD3G Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
20.47 kDa
20 µg/$150
CD3G Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
20.47 kDa
100 µg/$494
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).