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CD3G

CD3g molecule, gamma (CD3-TCR complex)

CD3G is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency.

Gene Name: CD3g molecule, gamma (CD3-TCR complex)
Synonyms: CD3G, CD3-GAMMA, CD3g antigen, T-cell receptor gamma chain, T-cell receptors gamma chain, T3G, T-cell receptor T3 gamma chain
Target Sequences: NM_000073 NP_000064.1 P09693

Publications (1)

1
Intrapulmonary Delivery of CpG Microparticles Eliminates Lung Tumors. Sato T, Shimosato T, Ueda A, Ishigatsubo Y, Klinman DM. Molecular cancer therapeutics. 2015 14:2198-205. (ICC, Flo; Mouse, Human) [Full Text Article] [PubMed:26206336] [PMC:PMC4596766]

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).