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CD3E

CD3e molecule, epsilon (CD3-TCR complex)

CD3E is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

Gene Name: CD3e molecule, epsilon (CD3-TCR complex)
Synonyms: CD3E, CD3e antigen, CD3-epsilon, T-cell receptor epsilon chain, TCRE, T-cell receptors epsilon chain, T3E, CD3 Epsilon, CD3
Target Sequences: NM_000733 NP_000724.1

Publications (1)

1
Inhibition of STAT3 augments antitumor efficacy of anti-CTLA-4 treatment against prostate cancer. Kristina Witt , Susan Evans-Axelsson, Andreas Lundqvist, Martin Johansson, Anders Bjartell, Rebecka Hellsten. Cancer immunology, immunotherapy : CII. 2021 Nov;;70:3155-3166. [Full Text Article] [PubMed:33786638] [PMC:PMC8505385] Related Antibodies: LS-C343957.

☰ Filters
Products
Proteins (22)
Over-Expression Lysate (2)
Recombinant (20)
CD3E (22)
SDS-PAGE (2)
No (22)
6His, C-terminus (2)
6His, N-terminus (2)
DDK (Flag)-His, C-terminus (1)
Fc, C-terminus (3)
Fc/6His,C-terminus (1)
Fc-AVI, C-terminus (1)
GST (1)
His (3)
His,C-terminus (3)
His-T7 (1)
Mouse IgG Fc, C-terminus (1)
Myc-DDK (Flag) (3)
Crab-eating macaque (1)
Human (19)
Mouse (1)
293E Cells (1)
293T Cells (1)
CHO Cells (1)
E. coli (3)
HEK 293 Cells (4)
Human (3)
Human Cells (3)
Mammalian Cells (3)
Wheat Germ Extract (1)
Yeast (2)
Purified (6)
Low endotoxin level (12)
Biologically active (1)
CD3E Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Yeast
6His, N-terminus
11.9 kDa
100 µg/$499; 20 µg/$364; 1 mg/$1,683
CD3E Protein
Select
CHO Cells
His,C-terminus
SDS-PAGE
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant human CD3E consists of 115 amino acids and predicts a molecular mass of 13.2 kDa.
50 µg/$395; 500 µg/$1,641
CD3E Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Yeast
6His, N-terminus
100 µg/$446; 20 µg/$336; 1 mg/$1,460
Select
Human Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
38.7kD
10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157
Select
E. coli
103 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
11.44 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
CD3E Protein - Using the Octet RED System, the affinity constant (Kd) of CD3 epsilon / CD3e Protein, Human, Recombinant (His Tag) bound to Human CD3 (humanized OKT3) Antibody-Human IgG4 was 3.8 nM.
Select
HEK 293 Cells
His,C-terminus
SDS-PAGE
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant human CD3E consists of 115 amino acids after removal of the signal peptide and has a predicted molecular mass of 13.2 kDa.
50 µg/$395; 500 µg/$1,641
CD3E Protein - Purified recombinant protein CD3E was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
20.7 kDa
20 µg/$1,107
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
12.79kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585
CD3E Protein - Recombinant T-Cell Surface Glycoprotein CD3 Epsilon By SDS-PAGE
Select
E. coli
His-T7
21.4 kDa
10 µg/$282; 50 µg/$447; 100 µg/$715; 200 µg/$892; 1 mg/$2,005; 500 µg/$1,543; 5 mg/$3,123; 2 mg/$2,192
CD3E Protein - 12.5% SDS-PAGE of human CD3E stained with Coomassie Blue
Select
Wheat Germ Extract
GST
46.09 kDa
10 µg/$479; 25 µg/$670
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
12.8 kDa
10 µg/$288; 50 µg/$436
Select
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
38 kDa
10 µg/$288; 50 µg/$436
CD3E Protein - Recombinant protein products for various applications-Elabscience
Select
Human
Fc-AVI, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
40.5 kDa
20 µg/$416; 100 µg/$910
CD3E Protein - Recombinant Human CD3 epsilon/CD3E (C-mFC)
Select
Human
Mouse IgG Fc, C-terminus
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
28.5 kDa
10 µg/$290; 50 µg/$446
CD3E Protein
Select
293E Cells
His,C-terminus
22.7 kDa
20 µg/$677
CD3E Protein - Recombinant Human CD3E&CD3G Heterodimer (C-Fc-6His&C-Fc-Flag)
Select
Human
Fc/6His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
39.2&38.1 kDa
10 µg/$356; 50 µg/$716
Select
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
38.7 kDa
10 µg/$281; 50 µg/$389
CD3E Protein
Select
HEK 293 Cells
DDK (Flag)-His, C-terminus
14 kDa
20 µg/$1,107
CD3E Protein
Select
E. coli
His
50 µg/$361; 250 µg/$739; 10 µg/$261
CD3E Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
23.15 kDa
20 µg/$150
CD3E Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
23.15 kDa
100 µg/$494
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
13.2 kDa
50 µg/$603; 500 µg/$3,389
Viewing 1-22 of 22 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).