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CD38

CD38 molecule

Synthesizes the second messangers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.

Gene Name: CD38 molecule
Synonyms: CD38, ADP-ribosyl cyclase 1, CD38 antigen (p45), CD38 antigen, Cyclic ADP-ribose hydrolase 1, T10, CADPr hydrolase 1, CD38 molecule, NAD(+) nucleosidase
Target Sequences: NM_001775 NP_001766.2 P28907

Publications (3)

1
CD38 is methylated in prostate cancer and regulates extracellular NAD. Mottahedeh J, Haffner MC, Grogan TR, Hashimoto T, Crowell PD, Beltran H, Sboner A, Bareja R, Esopi D, Isaacs WB, Yegnasubramanian S, Rettig MB, Elashoff DA, Platz EA, De Marzo AM, Teitell MA, Goldstein AS. Cancer & metabolism. 2018 September;6:13. [Full Text Article] [PubMed:30258629] [PMC:PMC6150989] Related Antibodies: LS-A9696.
2
SIV and Mycobacterium tuberculosis synergy within the granuloma accelerates the reactivation pattern of latent tuberculosis. Collin R Diedrich, Tara Rutledge, Pauline Maiello, Tonilynn M Baranowski, Alexander G White, H Jacob Borish, Paul Karell, Forrest Hopkins, Jessica Brown, Sarah M Fortune, JoAnne L Flynn, Zandrea Ambrose, Philana Ling Lin. PLoS pathogens. 2020 July;16:e1008413. [Full Text Article] [PubMed:32730321] [PMC:PMC7419014] Related Antibodies: LS-A9696.
3
Different Innate Immune Responses in BALB/c and C57BL/6 Strains following Corneal Transplantation. Tim Bleul, Xinyu Zhuang, Antonia Hildebrand, Clemens Lange, Daniel Böhringer, Günther Schlunck, Thomas Reinhard, Thabo Lapp. Journal of innate immunity. 2020 September;44501. [Full Text Article] [PubMed:32906119] [PMC:PMC7879253] Related Antibodies: LS-C43670.

☰ Filters
Products
Proteins (29)
Over-Expression Lysate (2)
Recombinant (27)
CD38 (29)
No (29)
6His, C-terminus (4)
6His, N-terminus (1)
6His-AVI, N-terminus (1)
Fc, C-terminus (5)
GST (1)
GST, N-terminus (1)
His (2)
His,C-terminus (4)
His-DDK (Flag) (1)
His-T7 (3)
Human IgG1 Fc, N-terminus (1)
mFc, C-terminus (2)
Mouse IgG2a Fc, N-terminus (1)
Myc-DDK (Flag) (2)
Crab-eating macaque (2)
Cynomolgus (1)
Human (16)
Mouse (6)
Rat (3)
293T Cells (1)
E. coli (4)
HEK 293 Cells (4)
Human (1)
Human Cells (2)
Mammalian Cells (15)
Wheat Germ Extract (2)
Purified (6)
Low endotoxin level (21)
CD38 Protein
Select
E. coli
6His, N-terminus
32 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
Select
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
56.9 kDa
10 µg/$248; 50 µg/$317
Select
HEK 293 Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
31.3 kDa
50 µg/$567; 500 µg/$2,696
CD38 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CD38 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
34.1 kDa
20 µg/$150
CD38 Protein - Recombinant  Cyclic ADP Ribose Hydrolase By SDS-PAGE
Select
E. coli
His-T7
28.8 kDa
10 µg/$275; 50 µg/$407; 100 µg/$652; 200 µg/$812; 1 mg/$1,893; 500 µg/$1,444; 5 mg/$2,843; 2 mg/$2,077
CD38 Protein - 12.5% SDS-PAGE of human CD38 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
58.52 kDa
10 µg/$479; 25 µg/$670
Select
Mammalian Cells
mFc, C-terminus
Less than 0.1 ng/mL (Less than 1 EU/µg) (determined by LAL method).
10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353
Select
Mammalian Cells
6His, C-terminus
Less than 0.1 ng/mL (Less than 1 EU/µg) (determined by LAL method).
10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353
Select
Mammalian Cells
6His, C-terminus
Less than 0.1 ng/mL (Less than 1 EU/µg) (determined by LAL method).
10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353
Select
Mammalian Cells
6His, C-terminus
Less than 0.1 ng/mL (Less than 1 EU/µg) (determined by LAL method).
10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353
Select
Mammalian Cells
6His, C-terminus
Less than 0.1 ng/mL (Less than 1 EU/µg) (determined by LAL method).
10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353
Select
Mammalian Cells
Fc, C-terminus
Less than 0.1 ng/mL (Less than 1 EU/µg) (determined by LAL method).
10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353
Select
Mammalian Cells
Fc, C-terminus
Less than 0.1 ng/mL (Less than 1 EU/µg) (determined by LAL method).
10 µg/$248; 50 µg/$321; 500 µg/$905; 1 mg/$1,245
Select
Mammalian Cells
mFc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
56.5 kDa
10 µg/$317; 50 µg/$524
Select
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
57 kDa
10 µg/$317; 50 µg/$524
Select
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
30.7 kDa
10 µg/$344; 50 µg/$584
Select
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
30.6 kDa
10 µg/$344; 50 µg/$584
Select
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
30.9 kDa
10 µg/$317; 50 µg/$524
Select
HEK 293 Cells
Mouse IgG2a Fc, N-terminus
Less than 5.0 EU/mg protein (determined by LAL method).
~70 kDa (SDS-PAGE)
100 µg/$463
Select
HEK 293 Cells
Human IgG1 Fc, N-terminus
Less than 5.0 EU/mg protein (determined by LAL method).
~70 kDa (SDS-PAGE)
100 µg/$463
CD38 Protein - Recombinant Human ADP-ribosyl Cyclase/cyclic ADP-ribose Hydrolase 1/CD38 (N-6His-Avi) Biotinylated
Select
Human
6His-AVI, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
33.3 kDa
20 µg/$416; 100 µg/$910
Select
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
57 kDa
10 µg/$406; 50 µg/$810
Select
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
30.8 kDa
10 µg/$317; 50 µg/$524
CD38 Protein - Recombinant Cyclic ADP Ribose Hydrolase By SDS-PAGE
Select
E. coli
His-T7
30.3 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
Viewing 1-25 of 29 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).