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CD34

CD34 molecule

CD34 is a monomeric cell surface antigen with a molecular mass of approximately 110 kD that is selectively expressed on human hematopoietic progenitor cells. CD34 is a member of a family of single-pass transmembrane sialomucin proteins that show expression on early hematopoietic and vascular-associated tissue. CD34 is also an important adhesion molecule and is required for T cells to enter lymph nodes. It is expressed on lymph node endothelia whereas the L-selectin to which it binds is on the T cell.

Gene Name: CD34 molecule
Synonyms: CD34, CD34 molecule, CD34 antigen, HPCA1
Target Sequences: NM_001773 NP_001764.1 P28906

Publications (12)

1
Characterization of MEC 14.7, a new monoclonal antibody recognizing mouse CD34: a useful reage for identifying and characterizing blood vessels and hematopoietic precursors. Garlanda C, Berthier R, Garin J, Stoppacciaro A, Ruco L, Vittet D, Gulino D, Matteucci C, Mantovani A, Vecchi A, Dejana E. European journal of cell biology. 1997 73:368-77. [PubMed:9270880]
2
A general strategy for isolation of endothelial cells from murine tissues. Characterization of two endothelial cell lines from the murine lung and subcutaneous sponge implants. Dong QG, Bernasconi S, Lostaglio S, De Calmanovici RW, Martin-Padura I, Breviario F, Garlanda C, Ramponi S, Mantovani A, Vecchi A. Arteriosclerosis, thrombosis, and vascular biology. 1997 17:1599-604. [PubMed:9301641]
3
Differential responsiveness to constitutive vs. inducible chemokines of immature and mature mouse dendritic cells. Vecchi A, Massimiliano L, Ramponi S, Luini W, Bernasconi S, Bonecchi R, Allavena P, Parmentier M, Mantovani A, Sozzani S. Journal of leukocyte biology. 1999 66:489-94. [PubMed:10496320]
4
Enrichment for living murine keratinocytes from the hair follicle bulge with the cell surface marker CD34. Trempus CS, Morris RJ, Bortner CD, Cotsarelis G, Faircloth RS, Reece JM, Tennant RW. The Journal of investigative dermatology. 2003 120:501-11. (ICC, IHC, Flo) [PubMed:12648211]
5
Organogenesis from dissociated cells: generation of mature cycling hair follicles from skin-derived cells. Zheng Y, Du X, Wang W, Boucher M, Parimoo S, Stenn K. The Journal of investigative dermatology. 2005 124:867-76. (IHC-P) [PubMed:15854024]
6
Generation and characterization of a mouse lymphatic endothelial cell line. Sironi M, Conti A, Bernasconi S, Fra AM, Pasqualini F, Nebuloni M, Lauri E, De Bortoli M, Mantovani A, Dejana E, Vecchi A. Cell and tissue research. 2006 325:91-100. [PubMed:16534603]
7
A subpopulation of mouse esophageal basal cells has properties of stem cells with the capacity for self-renewal and lineage specification. Kalabis J, Oyama K, Okawa T, Nakagawa H, Michaylira CZ, Stairs DB, Figueiredo JL, Mahmood U, Diehl JA, Herlyn M, Rustgi AK. The Journal of clinical investigation. 2008 118:3860-9. [PubMed:19033657] [PMC:PMC2579884]
8
The mobilization and effect of endogenous bone marrow progenitor cells in diabetic wound healing. Fiorina P, Pietramaggiori G, Scherer SS, Jurewicz M, Mathews JC, Vergani A, Thomas G, Orsenigo E, Staudacher C, La Rosa S, Capella C, Carothers A, Zerwes HG, Luzi L, Abdi R, Orgill DP. Cell transplantation. 2010 19:1369-81. [PubMed:20977829]
9
Endothelial cell HIF-1 and HIF-2 differentially regulate metastatic success. Branco-Price C, Zhang N, Schnelle M, Evans C, Katschinski DM, Liao D, Ellies L, Johnson RS. Cancer cell. 2012 21:52-65. [PubMed:22264788] [PMC:PMC3334270]
10
Effects of Sorafenib Dose on Acquired Reversible Resistance and Toxicity in Hepatocellular Carcinoma. Kuczynski EA, Lee CR, Man S, Chen E, Kerbel RS. Cancer research. 2015 June;75:2510-9. (Mouse) [Full Text Article] [PubMed:25908587]
11
Macrophages form functional vascular mimicry channels in vivo. Barnett FH, Rosenfeld M, Wood M, Kiosses WB, Usui Y, Marchetti V, Aguilar E, Friedlander M. Scientific reports. 2016 November;6:36659. (Mouse) [Full Text Article] [PubMed:27834402] [PMC:PMC5105153] Related Antibodies: LS-C62600.
12
Vascular endothelial growth inhibitor 174 is a negative regulator of aggressiveness and microvascular density in human clear cell renal cell carcinoma. Wu L, Li X, Ye L, Shayiremu D, Deng X, Zhang X, Jiang W, Yang Y, Gong K, Zhang N. Anticancer research. 2014 Feb;34:715-22. [Full Text Article] [PubMed:24511004] Related Antibodies: LS-B5262.
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Antibodies (256)
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CD34 (287)
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CD34 Antibody - Anti-CD34 antibody IHC of human kidney, glomerulus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unmodified form of this product. Other forms have not been tested.
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Cancer Pathology
Cancer
CD34 Mouse anti-Human Monoclonal (Azide-free) (QBEnd-10) Antibody
Human, Non-Human Primates
Flo, Func, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated, Azide-free
0.1 mg/$440
CD34 Antibody - Anti-CD34 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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CD34 Rat anti-Mouse Monoclonal (MEC14.7) Antibody
Mouse, Human
Flo, IHC, IHC-P, IP
Unconjugated
50 µg/$515
CD34 Antibody - Anti-CD34 antibody IHC of human kidney, endothelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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CD34 Mouse anti-Human Monoclonal Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
50 µg/$505
CD34 Antibody - Anti-CD34 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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CD34 Mouse anti-Human Monoclonal Antibody
Human
Flo, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
50 µg/$460
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CD34 Rat anti-Mouse Monoclonal (MEC14.7) Antibody
Mouse
ELISA, Flo, IF, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
250 µg/$371; 500 µg/$445
CD34 Antibody - Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CD34 Rabbit anti-Human Polyclonal (aa366-382) Antibody
Mouse, Rat, Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated
50 µg/$440
CD34 Antibody - CD34 Antibody (MEC 14.7) - Hematopoietic Stem Cell Marker - IHC of CD34 on mouse renal cancer xenograft.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CD34 Rat anti-Mouse Monoclonal (MEC14.7) Antibody
Mouse, Rat
ELISA, Flo, ICC, IF, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
0.1 ml/$376
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CD34 Goat anti-Pig Polyclonal (Extracellular Domain) Antibody
Pig
ELISA, WB
Unconjugated
100 µg/$809
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CD34 Chicken anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$418
CD34 Antibody - Anti-CD34 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
Cancer Pathology
Cancer
CD34 Mouse anti-Human Monoclonal (4H11[APG]) Antibody
Human
Flo, ICC, IHC, IHC-P, WB
Unconjugated
0.1 mg/$440
CD34 Antibody - Anti-CD34 antibody IHC of human kidney, glomeruli. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:800.
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CD34 Mouse anti-Human Monoclonal (Concentrated) (QBEND-10) Antibody
Human
Flo, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated, Concentrated
50 µg/$585
CD34 Antibody - Anti-CD34 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CD34 Mouse anti-Human Monoclonal (FITC) Antibody
Human
Flo, IHC, IHC-Fr, IHC-P
FITC Conjugated
25 Tests/$460
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CD34 Mouse anti-Human Monoclonal (FITC) Antibody
Human
Flo, IHC, WB
FITC Conjugated
120 Tests/$650
CD34 Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CD34 Rabbit anti-Human Monoclonal (EP88) Antibody
Human
IHC, IHC-Fr, IHC-P
Unconjugated
50 µl/$440
Select
CD34 Mouse anti-Dog Monoclonal (1H6) Antibody
Dog
Flo, WB
Unconjugated
0.1 mg/$374
Select
CD34 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
Flo, ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$381
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CD34 Rat anti-Mouse Monoclonal (MEC14.7) Antibody
Mouse
ELISA, Flo, IF, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
100 µg/$639
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CD34 Rat anti-Mouse Monoclonal (Concentrated) (MEC14.7) Antibody
Mouse
ELISA, Flo, IF, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated, Concentrated
1 ml/$510
CD34 Antibody - Immunohistochemistry of paraffin-embedded human colon cancer at dilution of 1:100
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CD34 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$284; 100 µg/$348
CD34 Antibody - Formalin-fixed, paraffin-embedded human tonsil stained with CD34 antibody (QBEnd/10 + HPCA1/763).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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CD34 Mouse anti-Human Monoclonal (N-Terminus) (Azide-free, BSA-free) (QBEnd/10 + HPCA1/763) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$550
Select
CD34 Mouse anti-Human Monoclonal (aa185-214) (PE) Antibody
Human
IHC, WB
PE Conjugated
200 µl/$836
CD34 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
CD34 Mouse anti-Human Monoclonal (aa185-214) (132CT29.1.5) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
200 µl/$460
CD34 Antibody - Anti-CD34 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 20 ug/ml.
Select
CD34 Mouse anti-Human Monoclonal (4H11) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
50 µg/$440
Select
CD34 Rat anti-Mouse Monoclonal (RPE) (MEC14.7) Antibody
Mouse
Flo
RPE Conjugated
100 Tests/$456
Select
CD34 Rat anti-Mouse Monoclonal (PE) (MEC14.7) Antibody
Mouse
Flo
PE Conjugated
50 µg/$294; 300 µg/$527
Viewing 1-25 of 287 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).