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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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CD32B
Fc fragment of IgG, low affinity IIb, receptor (CD32)
Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
| Gene Name: | Fc fragment of IgG, low affinity IIb, receptor (CD32) |
| Family/Subfamily: | Immunoglobulin , not assigned-Immunoglobulin |
| Synonyms: | FCGR2B, CD32, CD32 antigen, CD32B, CDw32, FCG2, FcRII-b, IgG Fc receptor II-b, Fc gamma RIIb, Fc-gamma RII-b, FCGR2, Fc-gamma-RIIb, IGFR2 |
| Target Sequences: | NM_004001 NP_003992.3 P31994 |
Publications (1)
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