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CD2BP2

CD2 (cytoplasmic tail) binding protein 2

CD2BP2 is a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined.

Gene Name: CD2 (cytoplasmic tail) binding protein 2
Synonyms: CD2BP2, CD2 tail-binding protein 2, KIAA1178, FWP010, Snu40, U5 snRNP 52K protein, U5-52K, PPP1R59, LIN1
Target Sequences: NM_006110 NP_006101.1 O95400

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).