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CD247 / CD3 Zeta
CD247 molecule
CD247 / CD3 Zeta is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
| Gene Name: | CD247 molecule |
| Synonyms: | CD247, CD3 Zeta, CD3H, CD3Z, CD247 antigen, zeta subunit, CD247 molecule, CD3zeta chain, T3Z, TCR zeta chain, TCRZ, T-cell receptor T3 zeta chain, CD247 antigen, CD3-ZETA, CD3Q |
| Target Sequences: | NM_000734 NP_000725.1 P20963 |
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