Products
Services
Research Areas
Resources
Contact Us
Distributors
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Services
Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Reasearch Areas
Cell Cycle Pathways
Protein Family And Group
Contact Us
LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
206-374-1102 (International)
Fax:
866-206-6909 (Toll Free North America)
206-577-4565 (International)
How To Buy - Details about how to buy our products.
Orders@LSBio.com - To submit a new order.
Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, froforma invoice requests, or other billing issues.
Technical.Support@LSBio.com - To request technical information about an LSBio product or its applications
Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.
Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

CD1C

CD1c molecule

CD1C is a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.

Gene Name: CD1c molecule
Synonyms: CD1C, BDCA1, CD1, CD1c molecule, CD1C antigen, c polypeptide, CD1c antigen, R7
Target Sequences: NM_001765 NP_001756.2 P29017

Publications (1)

1
Splenic proliferative lymphoid nodules distinct from germinal centers are sites of autoantigen stimulation in immune thrombocytopenia. Daridon C, Loddenkemper C, Spieckermann S, Kühl AA, Salama A, Burmester GR, Lipsky PE, Dörner T. Blood. 2012 120:5021-31. (IP; Human) [Full Text Article] [PubMed:22955923]

Filtered by: None
Target
CD1C (55)
Reactivity
Human (55)
Mouse (2)
Rat (2)
Dog (2)
Monkey (2)
Application
IHC (22)
IHC-Fr (4)
IHC-P (7)
WB (41)
Flo (12)
ELISA (18)
IF (18)
IP (4)
Host
rabbit (21)
mouse (33)
goat (1)
Isotype
IgG (15)
IgG1 (24)
IgG1,k (6)
IgG2a,k (1)
IgG2b (2)
Clonality
monoclonal mc (33)
polyclonal pc (22)
Clone
2A7C11 (1)
3G1B3 (1)
4B11 (1)
4C7 (2)
L161 (4)
M241 (5)
OTI1E10 (2)
OTI1F4 (2)
OTI1H9 (2)
OTI2B3 (2)
OTI2D4 (2)
OTI2F1 (2)
OTI2F4 (2)
OTI5A8 (2)
OTI5B8 (2)
Format
AP Conjugated (1)
APC Conjugated (2)
Azide-free (2)
Biotin Conjugated (5)
Carrier-free (10)
FITC Conjugated (5)
HRP Conjugated (3)
PE Conjugated (2)
RPE Conjugated (1)
Unconjugated (36)
Epitope
aa226-253 (8)
aa227-276 (4)
211-260 aa, Internal (1)
aa19-302 (1)
Publications
No (55)
Showing 1-25 of 55 results

IHC-plus™ CD1C Antibody (clone 4C7) LS-B10059
Mouse Monoclonal [clone 4C7] (IgG1) to Human CD1C
Human
IF, IHC, IHC-P, WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-CD1C antibody IHC staining of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-CD1C mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CD1C.

CD1C Antibody (clone OTI1H9) LS-C174299
Mouse Monoclonal [clone OTI1H9] (IgG1) to Human CD1C
Human
IF, IHC, IHC-P, WB
Unconjugated
100µl  $345.00
IHC of paraffin-embedded Human prostate tissue using anti-CD1C mouse monoclonal antibody.
IHC of paraffin-embedded Human lymphoma tissue using anti-CD1C mouse monoclonal antibody.

CD1C Antibody (clone OTI1H9, Carrier-free) LS-C799973
Mouse Monoclonal [clone OTI1H9] (IgG1) to Human CD1C
Human
IF, IHC, WB
Unconjugated, Carrier-free
100µg  $395.00

CD1C Antibody (clone M241, Azide-free) LS-C134218
Mouse Monoclonal [clone M241] (IgG1,k) to Human CD1C
Human
Flo, IHC, IHC-Fr
Unconjugated, Azide-free
100µg 1mg/ml  $315.00
Flow cytometry of CD1C antibody This image was taken for the unmodified form of this product. Other forms have not been tested.

CD1C Antibody (clone OTI2B3) LS-C337876
Mouse Monoclonal [clone OTI2B3] (IgG1) to Human CD1C
Human
IF, IHC, IHC-P, WB
Unconjugated
100µl  $345.00
IHC of paraffin-embedded Human prostate tissue using anti-CD1C mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
IHC of paraffin-embedded Human lymphoma tissue using anti-CD1C mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).

CD1C Antibody (clone OTI2B3, Carrier-free) LS-C787577
Mouse Monoclonal [clone OTI2B3] (IgG1) to Human CD1C
Human
IF, IHC, WB
Unconjugated, Carrier-free
100µg  $395.00

CD1C Antibody (clone M241, FITC) LS-C134216
Mouse Monoclonal [clone M241] (IgG1,k) to Human CD1C
Human
Flo, IHC, IHC-Fr
FITC Conjugated
120tst  $345.00
Flow cytometry of CD1C antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.

CD1C Antibody (clone OTI1F4) LS-C337874
Mouse Monoclonal [clone OTI1F4] (IgG1) to Human CD1C
Human
IF, IHC, IHC-P, WB
Unconjugated
100µl 1mg/ml  $345.00
IHC of paraffin-embedded Human lymphoma tissue using anti-CD1C mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
IHC of paraffin-embedded Human tonsil using anti-CD1C mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).

CD1C Antibody (clone OTI1F4, Carrier-free) LS-C787571
Mouse Monoclonal [clone OTI1F4] (IgG1) to Human CD1C
Human
IF, IHC, WB
Unconjugated, Carrier-free
100µg  $395.00

CD1C Antibody (clone OTI2D4) LS-C337875
Mouse Monoclonal [clone OTI2D4] (IgG1) to Human CD1C
Human
IF, IHC, IHC-P, WB
Unconjugated
100µl 1mg/ml  $345.00
IHC of paraffin-embedded Human lymphoma tissue using anti-CD1C mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
IHC of paraffin-embedded Human tonsil using anti-CD1C mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).

CD1C Antibody (clone OTI2D4, Carrier-free) LS-C787573
Mouse Monoclonal [clone OTI2D4] (IgG1) to Human CD1C
Human
IF, IHC, WB
Unconjugated, Carrier-free
100µg  $395.00

CD1C Antibody (Biotin) LS-C35348
Mouse Monoclonal (IgG1,k) to Human CD1C
Human
Flo
Biotin Conjugated
100µg  $495.00

CD1C Antibody (aa19-302) LS-C127307
Goat Polyclonal (IgG) to Human CD1C
Human
ELISA, WB
Unconjugated
100µg  $740.00

CD1C Antibody (clone OTI1E10) LS-C174309
Mouse Monoclonal [clone OTI1E10] (IgG1) to Human CD1C
Mouse, Dog, Rat, Human, Monkey
WB
Unconjugated
100µl 1mg/ml  $345.00
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CD1C (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CD1C.
Western blot of extracts (35 ug) from 9 different cell lines by using anti-CD1C monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).

CD1C Antibody (aa226-253) LS-C168518
Rabbit Polyclonal to Human CD1C
Human
WB
Unconjugated
400µl  $325.00
CD1C Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The CD1C antibody detected the CD1C protein (arrow).
Western blot of CD1C (arrow) using rabbit polyclonal CD1C Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CD1C gene.

CD1C Antibody (clone 3G1B3) LS-C682645
Mouse Monoclonal [clone 3G1B3] (IgG2b) to Human CD1C
Human
ELISA, Flo, IHC, WB
Unconjugated
100µl  $365.00

CD1C Antibody (clone 2A7C11) LS-C682650
Mouse Monoclonal [clone 2A7C11] (IgG2b) to Human CD1C
Human
ELISA, Flo, IHC, WB
Unconjugated
100µl  $365.00

CD1C Antibody LS-C675482
Rabbit Polyclonal (IgG) to Human CD1C
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µl  $235.00; 100µl  $285.00
Immunohistochemistry of paraffin-embedded human spleen tissue at dilution 1:100
Immunohistochemistry of paraffin-embedded human tonsil tissue at dilution 1:100

CD1C Antibody (clone OTI2F4) LS-C337877
Mouse Monoclonal [clone OTI2F4] (IgG1) to Human CD1C
Human
IHC, IHC-P, WB
Unconjugated
100µl 1mg/ml  $345.00
IHC of paraffin-embedded Human lymph node tissue using anti-CD1C mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
IHC of paraffin-embedded Human tonsil using anti-CD1C mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).

CD1C Antibody (clone OTI2F4, Carrier-free) LS-C787591
Mouse Monoclonal [clone OTI2F4] (IgG1) to Human CD1C
Human
IF, IHC, WB
Unconjugated, Carrier-free
100µg  $395.00

CD1C Antibody (clone 4C7, Carrier-free) LS-C787572
Mouse Monoclonal [clone 4C7] (IgG1) to Human CD1C
Human
IF, IHC, WB
Unconjugated, Carrier-free
100µg  $395.00

CD1C Antibody (clone L161) LS-C662843
Mouse Monoclonal [clone L161] (IgG1) to Human CD1C
Human
Flo, IHC, IP
Unconjugated
0.1mg 1mg/ml  $255.00

CD1C Antibody (clone L161, PE) LS-C662873
Mouse Monoclonal [clone L161] (IgG1) to Human CD1C
Human
Flo, IHC, IP
PE Conjugated
100tst  $315.00

CD1C Antibody (clone OTI5A8) LS-C174307
Mouse Monoclonal [clone OTI5A8] (IgG1) to Human CD1C
Human
IF, WB
Unconjugated
100µl 1mg/ml  $345.00
Anti-CD1C mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CD1C.
Western blot of extracts (35 ug) from 9 different cell lines by using g anti-CD1C monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).

CD1C Antibody LS-C677428
Rabbit Polyclonal (IgG) to Human CD1C
Human
ELISA, IF, WB
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunofluorescent analysis of A549 cells diluted at 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Western Blot Positive WB detected in:Mouse heart tissue All Lanes:CD1C antibody at 3µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 38 KDa Observed band size: 38 KDa
Showing 1-25 of 55 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).