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CD151

CD151 molecule (Raph blood group)

CD151 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene.

Gene Name:	CD151 molecule (Raph blood group)
Family/Subfamily:	Tetraspan , not assigned-Tetraspan
Synonyms:	CD151, CD151 antigen, gp27, Membrane glycoprotein SFA-1, PETA3, RAPH, SFA-1, TSPAN24, PETA-3, SFA1, MER2, Tetraspanin-24, Tspan-24
Target Sequences:	NM_004357 NP_004348.2 P48509

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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