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CD121b / IL1R2

interleukin 1 receptor, type II

Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.

Gene Name: interleukin 1 receptor, type II
Family/Subfamily: Interleukin
Synonyms: IL1R2, CD121b, CD121b antigen, CDw121b, IL-1RT-2, IL1R2c, Interleukin-1 receptor beta, Interleukin-1 receptor type II, IL-1R-beta, Antigen CDw121b, IL-1 type II receptor, IL-1R-2, IL-1RT2, IL1RB, Interleukin-1 receptor type 2
Target Sequences: NM_004633 NP_004624.1 P27930

Publications (1)

1
Altered activation state of circulating neutrophils in patients with neovascular age-related macular degeneration. Marie Krogh Nielsen, Sven Magnus Hector, Kelly Allen, Yousif Subhi, Torben Lykke Sørensen. Immunity & ageing : I & A. 2017 Jul;14:18. [Full Text Article] [PubMed:28769990] [PMC:PMC5531023] Related Antibodies: LS-C139986.

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Products
ELISA Kits (24)
Custom (3)
Sandwich (19)
Sandwich CLIA (2)
CD121b / IL1R2 (24)
Human (10)
Mouse (3)
Rat (4)
Chicken (1)
Guinea pig (1)
Monkey (1)
Porcine (1)
Rabbit (1)
Rhesus monkey (1)
Sheep (1)
12 x 8-Well Microstrips (3)
96-Well Microplate (5)
96-Well Strip Plate (16)
No (24)
Cell Culture Supernatants (3)
Cell Lysates (1)
Plasma (14)
Serum (16)
Tissue Homogenates (5)
CD121b / IL1R2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$782
CD121b / IL1R2 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Serum
1 Plate/$717
CD121b / IL1R2 ELISA Kit
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Sandwich
96-Well Microplate
Mouse
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
CD121b / IL1R2 ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
CD121b / IL1R2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Guinea pig
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
CD121b / IL1R2 ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
CD121b / IL1R2 ELISA Kit
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Sandwich
96-Well Strip Plate
Porcine
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
CD121b / IL1R2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Sheep
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$760
CD121b / IL1R2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
CD121b / IL1R2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CD121b / IL1R2 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
12.5 - 800 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
CD121b / IL1R2 ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
CD121b / IL1R2 ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
CD121b / IL1R2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$685
CD121b / IL1R2 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Serum
1 Plate/$795
CD121b / IL1R2 ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
CD121b / IL1R2 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
CD121b / IL1R2 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Rat
0.156 - 10 ng/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
CD121b / IL1R2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CD121b / IL1R2 ELISA Kit
Select
Custom
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$870
CD121b / IL1R2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rhesus monkey
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$940
CD121b / IL1R2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$764
CD121b / IL1R2 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
4.113 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$588
CD121b / IL1R2 ELISA Kit
Select
Sandwich
12 x 8-Well Microstrips
Human
32 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$618
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).