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CD105

endoglin

CD105 is a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: endoglin
Synonyms: ENG, CD105, CD105 antigen, END, HHT1, ORW, ORW1, Osler-Rendu-Weber syndrome 1, Endoglin
Target Sequences: NM_000118 NP_000109.1 P17813

Publications (2)

1
Differential expression of CD44 and CD24 markers discriminates the epitheliod from the fibroblastoid subset in a sarcomatoid renal carcinoma cell line: evidence suggesting the existence of cancer stem cells in both subsets as studied with sorted cells. Hsieh CH, Hsiung SC, Yeh CT, Yen CF, Chou YW, Lei WY, Pang ST, Chuang CK, Liao SK. Oncotarget. 2017 8:15593-15609. (WB; Human) [Full Text Article] [PubMed:28121626] [PMC:PMC5362508]
2
Angiogenic response in an in vitro model of dog microvascular endothelial cells stimulated with antigenic extracts from Dirofilaria immitis adult worms. Tatiana Zueva, Rodrigo Morchón, Elena Carretón, José Alberto Montoya-Alonso, Alexis Santana, María Dolores Bargues, Santiago Mas-Coma, Alicia Rodríguez-Barbero, Fernando Simón. Parasites & vectors. 2019 June;12:315. [Full Text Article] [PubMed:31234915] [PMC:PMC6591997]

☰ Filters
Products
Proteins (22)
Over-Expression Lysate (4)
Recombinant (18)
CD105 (22)
No (22)
6His, N-terminus (1)
Fc, C-terminus (1)
GST (2)
His (8)
His, N-Terminal (1)
His,C-terminus (1)
Myc-DDK (Flag) (6)
TRX, N-terminus (1)
TRX-6His, N-terminus (1)
Human (16)
Mouse (3)
Rat (1)
293T Cells (2)
E. coli (11)
HEK 293 Cells (6)
Human Cells (1)
Wheat Germ Extract (2)
Purified (4)
Low endotoxin level (6)
CD105 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
67.78 kDa
100 µg/$710
CD105 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
70.64 kDa
100 µg/$494
Select
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
61.2 kDa
100 µg/$1,070
CD105 Protein
Select
E. coli
His
20 µg/$361; 100 µg/$739; 4 µg/$261
CD105 Protein - 12.5% SDS-PAGE of human ENG stained with Coomassie Blue
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Wheat Germ Extract
GST
95.26 kDa
10 µg/$479; 25 µg/$670
CD105 Protein - 12.5% SDS-PAGE of human ENG stained with Coomassie Blue
Select
Wheat Germ Extract
GST
98.12 kDa
10 µg/$479; 25 µg/$670
CD105 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
67.78 kDa
20 µg/$215
CD105 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
70.64 kDa
20 µg/$150
CD105 Protein - Purified recombinant protein ENG was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
65 kDa
20 µg/$1,107
CD105 Protein - Purified recombinant protein ENG was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
68 kDa
20 µg/$1,107
Select
E. coli
299 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
33 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
Select
E. coli
TRX, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
33.6 kDa
10 µg/$376; 50 µg/$526
Select
HEK 293 Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
87.5 kDa
50 µg/$721
Select
E. coli
TRX-6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
33.6kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
Select
E. coli
6His, N-terminus
63 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
62.3 kDa
50 µg/$721
CD105 Protein - Recombinant Endoglin (ENG) by WB
Select
E. coli
His, N-Terminal
14.0kDa
10 µg/$267; 50 µg/$352; 200 µg/$702; 100 µg/$562; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,838
Select
E. coli
His
13.9 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
Select
E. coli
His
13.8 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
Select
E. coli
His
13.7 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
CD105 Protein - Recombinant Endoglin By SDS-PAGE
Select
E. coli
His
13.5 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
CD105 Protein - Recombinant Endoglin By SDS-PAGE
Select
E. coli
His
14.0 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).