CCR8 / CD198

chemokine (C-C motif) receptor 8

CCR8 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region.

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Proteins (2)

Type

Recombinant (2)

Target

CCR8 / CD198 (2)

Publications

No (2)

Tag

10His, N-terminus (1)

GST (1)

Species

Human (1)

Mouse (1)

Source

E. coli (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human CCR8 / CD198 Protein (Recombinant GST) (Full Length) - LS-G27960

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

67.2 kDa

Price:

2 µg/$439

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Mouse CCR8 / CD198 Protein (Recombinant 10His, N-terminus) (Full Length) - LS-G137420

Source:

E. coli

Tag:

10His, N-terminus

Price:

100 µg/$1,801; 20 µg/$1,247

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