Menu
Products
Services
Research Areas
Resources
Contact Us
Distributors
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Services
Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Contact Us
LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
206-374-1102 (International)
Fax:
866-206-6909 (Toll Free North America)
206-577-4565 (International)
How To Buy - Details about how to buy our products.
Orders@LSBio.com - To submit a new order.
Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, froforma invoice requests, or other billing issues.
Technical.Support@LSBio.com - To request technical information about an LSBio product or its applications
Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.
Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

CCR7

chemokine (C-C motif) receptor 7

CCR7, a Chemokine Receptor, is involved in lymphocyte recirculation through secondary lymphoid organs and moving lymphocytes and dendritic cells into distinct tissue compartments. CCR7 is called the Epstein-Barr-induced receptor because it mediates Epstein-Barr viral effects on B lymphocytes. CCR7 expression is up-regulated in mature dendritic cells, B cells infected with EBV, and in CD4+ cells infected with human herpes virus 6 and 7. Immature dendritic cells have been shown to express chemokine receptor 5 (CCR5) and migrate in response to macrophage inflammatory protein-1alpha (MIP-1alpha), whereas mature dendritic cells switch to CCR7 expression and respond exclusively to MIP-3beta and 6Ckine. Maturing dendritic cells upregulate CCR7, which drives their migration to the T-cell areas of the draining lymph nodes where antigen is presented to naive T cells.

Gene Name: chemokine (C-C motif) receptor 7
Family/Subfamily: GPCR , Chemokine
Synonyms: CCR7, BLR2, Chemokine (C-C) receptor 7, CD197, C-C CKR-7, CMKBR7, CC chemokine receptor 7, CCR-7, CD197 antigen, CDw197, EBI1, EVI1, MIP-3 beta receptor, C-c chemokine receptor 7, C-C chemokine receptor type 7, CC-CKR-7, Chemokine c-c motif receptor 7
Target Sequences: NM_001838 NP_001829.1 P32248

Publications (1)

1
Constitutive expression of the alpha4 integrin correlates with tumorigenicity and lymph node metastasis of the B16 murine melanoma. Rebhun RB, Cheng H, Gershenwald JE, Fan D, Fidler IJ, Langley RR. Neoplasia (New York, N.Y.). 2010 12:173-82. (WB) [PubMed:20126475] [PMC:PMC2814355]

Viewing 1-25 of 78 items
CCR7 Antibody - Anti-CCR7 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Neuroscience
Fast Shipping
Rabbit Polyclonal to Human CCR7
Bovine, Human, Monkey
IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
CCR7 Antibody - Anti-CCR7 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 14 ug/ml.
Select
Fast Shipping
Rabbit Polyclonal to Human CCR7
Bovine, Horse, Bat, Human, Monkey
ICC, IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
CCR7 Antibody - Anti-CCR7 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 14 ug/ml.
Select
Fast Shipping
Rabbit Polyclonal to Human CCR7
Bovine, Horse, Bat, Human, Monkey
ICC, IHC, IHC-P
Biotin Conjugated
100µl   $650.00
CCR7 Antibody - Anti-CCR7 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 14 ug/ml.
Select
Fast Shipping
Rabbit Polyclonal to Human CCR7
Bovine, Horse, Bat, Human, Monkey
ICC, IHC, IHC-P
FITC Conjugated
100µl   $650.00
CCR7 Antibody - Anti-CCR7 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 14 ug/ml.
Select
Fast Shipping
Rabbit Polyclonal to Human CCR7
Bovine, Horse, Bat, Human, Monkey
ICC, IHC, IHC-P
APC Conjugated
100µl   $650.00
CCR7 Antibody - Anti-CCR7 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 14 ug/ml.
Select
Fast Shipping
Rabbit Polyclonal to Human CCR7
Bovine, Horse, Bat, Human, Monkey
ICC, IHC, IHC-P
AP Conjugated
100µl   $650.00
CCR7 Antibody - Anti-CCR7 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 14 ug/ml.
Select
Fast Shipping
Rabbit Polyclonal to Human CCR7
Bovine, Horse, Bat, Human, Monkey
ICC, IHC, IHC-P
HRP Conjugated, Azide-free
100µl   $650.00
CCR7 Antibody - Anti-CCR7 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 14 ug/ml.
Select
Fast Shipping
Rabbit Polyclonal to Human CCR7
Bovine, Horse, Bat, Human, Monkey
ICC, IHC, IHC-P
PE Conjugated
100µl   $650.00
CCR7 Antibody - Anti-CCR7 antibody IHC staining of human lymph node. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Neuroscience
Fast Shipping
Rabbit Polyclonal to Human CCR7
Human
IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
Select
Goat Polyclonal to Mouse CCR7
Mouse
ELISA, Flo, IHC, IP, WB
Unconjugated
200µg   $475.00
CCR7 Antibody - Anti-CCR7 antibody IHC staining of human tonsil, lymphocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Neuroscience
Fast Shipping
Rabbit Polyclonal to Human CCR7
Human
IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
CCR7 Antibody - Staining of normal human peripheral blood cells with FITC anti-human CD45RA (HI100) (LS-C106037) and 1 ug of Biotin Rat IgG2a isotype control (left) or 1 ug of Biotin anti-human CCR7 (right) followed by Streptavidin-PE. Cells in the lymphocyte gate were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rat Monoclonal [clone 3D12] (IgG2a,k) to Human CCR7
Human
Flo
Biotin Conjugated
25µg   $225.00; 100µg   0.5mg/ml   $335.00
CCR7 Antibody - Staining of normal human peripheral blood cells with FITC anti-human CD45RA (HI100) (LS-C106037) and 0.125 ug of APC Rat IgG2a isotype control (left) or APC anti-human CCR7 (3D12) (right). Cells in the lymphocyte gate were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rat Monoclonal [clone 3D12] (IgG2a,k) to Human CCR7
Human
Flo
APC Conjugated
25tst   $255.00; 100tst   $385.00
CCR7 Antibody - Staining of normal human peripheral blood cells with APC anti-human CD45RA (HI100) (LS-C107334) and 0.125 ug of PE Rat IgG2a isotype control. Cells in the lymphocyte gate were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rat Monoclonal [clone 3D12] (IgG2a,k) to Human CCR7
Human
Flo
PE Conjugated
25tst   $235.00; 100tst   $335.00
Select
Rat Monoclonal (IgG2a) to Mouse CCR7
Mouse
Flo, Func, IHC, Neut
Unconjugated
100µg   $680.00
CCR7 Antibody - Immunohistochemistry of paraffin-embeddedi mouse spleen stained with Goat anti-mouse CD197
Select
Goat Polyclonal (IgG) to Mouse CCR7
Mouse
ELISA, Flo, IHC-P, WB
Unconjugated
50µg   $425.00
CCR7 Antibody - All lanes: Anti-CCR7 Antibody (N-term) at 1:4000 dilution Lane 1: K562 whole cell lysate Lane 2: Daudi whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 43 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Select
Mouse Monoclonal [clone 1987CT875.52.22] (IgG1,k) to Human CCR7
Human
ELISA, WB
Unconjugated
200µl   $325.00
CCR7 Antibody - Immunohistochemistry analysis of human lung tissue at a dilution of 1:100
Select
Rabbit Polyclonal (IgG) to Human CCR7
Human
ELISA, ICC, IF, IHC
Unconjugated
50µg   $285.00; 100µg   $385.00
CCR7 Antibody - CCR7 Antibody (Ascites)western blot of HL-60 cell line lysates (35 ug/lane). The CCR7 antibody detected the CCR7 protein (arrow).
Select
Mouse Monoclonal (IgG1) to Human CCR7
Human
WB
Unconjugated
0.1ml   $325.00
CCR7 Antibody - Staining of C57Bl/6 splenocytes with FITC anti-mouse CD4 (GK1.5) (LS-C106029) and 0.5 ug of APC Rat IgG2a isotype control. Cells were stained at 37uC for 0.5 hours and Fc receptor binding was blocked by staining cells with 5 ug/million cells anti-mouse CD16/32 (LS-C107169). Cells in the lymphocyte gate were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rat Monoclonal [clone 4B12] (IgG2a,k) to Mouse CCR7
Mouse
Flo
APC Conjugated
10µg   $195.00; 50µg   $305.00; 100µg   0.2mg/ml   $385.00
CCR7 Antibody - Staining of C57Bl/6 splenocytes with FITC anti-mouse CD3e (145-2C11) (LS-C105774) and 1 ug of PE-Cy7 Rat IgG2a isotype control. Cell staining was carried out at 37uC. Total viable cells were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rat Monoclonal [clone 4B12] (IgG2a,k) to Mouse CCR7
Mouse
Flo
PE, Cy7 Conjugated
10µg   $205.00; 50µg   $365.00; 100µg   0.2mg/ml   $435.00
CCR7 Antibody - Immunohistochemistry of CCR7 in human spleen tissue with CCR7 antibody at 5 µg/mL.
Select
Rabbit Polyclonal (IgG) to Human CCR7
Human
ELISA, IF, IHC, WB
Unconjugated
0.1mg   1mg/ml   $365.00
CCR7 Antibody - Western blot analysis of extracts of various cell lines, using CCR7 antibody.
Select
Rabbit Polyclonal (IgG) to Human CCR7
Mouse, Rat, Human
WB
Unconjugated
50µl   $235.00; 100µl   $315.00; 200µl   $425.00
CCR7 Antibody - Western blot analysis using CD197 mAb against HEK293 (1) and CD197 (AA: extra mix)-hIgGFc transfected HEK293 (2) cell lysate.
Select
Mouse Monoclonal [clone 7A5A9] (IgG1) to Human CCR7
Human
ELISA, Flo, WB
Unconjugated
100µl   $365.00
CCR7 Antibody - Western blot analysis using CD197 mAb against human CD197 (AA: extra mix) recombinant protein. (Expected MW is 37.5 kDa)
Select
Mouse Monoclonal [clone 4B7B8] (IgG1) to Human CCR7
Human
ELISA, Flo, WB
Unconjugated
100µl   $365.00

Viewing 1-25 of 78 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).