CCR5

chemokine (C-C motif) receptor 5 (gene/pseudogene)

CCR5 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene.

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Products

Proteins (6)

Type

Over-Expression Cell Culture Supernatant (1)

Over-Expression Lysate (2)

Recombinant (3)

Target

CCR5 (6)

Publications

No (6)

Tag

6His, N-terminus (2)

GST (1)

His (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Mouse (1)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Yeast (1)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (1)

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Human CCR5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80181

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

40.3 kDa

Price:

20 µg/$150

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Mouse CCR5 Protein (Recombinant 6His, N-terminus) (aa263-354) - LS-G57135

Source:

Yeast

Tag:

6His, N-terminus

Price:

100 µg/$499; 20 µg/$364; 1 mg/$1,683

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CCR5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123099

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

40.3 kDa

Price:

100 µg/$494

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Human CCR5 Protein (Over-Expression Cell Culture Supernatant 6His, N-terminus) (Asp20-Leu476) - LS-G26881

Source:

HEK 293 Cells

Tag:

6His, N-terminus

Molecular Weight:

55 kDa

Price:

200 µl/$283

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Human CCR5 Protein (Recombinant GST) (Full Length) - LS-G27961

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

66.9 kDa

Price:

2 µg/$439

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Human CCR5 Protein (Recombinant His) (aa172-352) - LS-G140963

Source:

E. coli

Sequence Length:

180 AA

Tag:

His

Endotoxin Level:

Less than 0.1 EU/µg protein (determined by LAL method).

Molecular Weight:

19.91 kDa

Price:

10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531

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