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CCNT1 / Cyclin T1

cyclin T1

CCNT1 / Cyclin T1 is a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner are also involved in triggering transcript elongation through phosphorylation of the carboxy-terminal domain of the largest RNA polymerase II subunit. Overexpression of this gene is implicated in tumor growth. Alternative splicing results in multiple transcript variants.

Gene Name: cyclin T1
Synonyms: CCNT1, CCNT, CDK9-associated C-type protein, Cyclin T1b, CYCT1, Cyclin T1, HIVE1, Cyclin C-related protein, Cyclin-T, Cyclin-T1
Target Sequences: NM_001240 NP_001231.2 O60563

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Products
Antibodies (30)
Primary (30)
CCNT1 / Cyclin T1 (30)
Human (30)
Mouse (13)
Rat (6)
Bat (3)
Bovine (3)
Chimpanzee (3)
Gibbon (3)
Goat (3)
Guinea pig (3)
Hamster (3)
Horse (3)
Monkey (3)
Pig (3)
Rabbit (3)
Xenopus (3)
IHC (10)
IHC-P (5)
WB (25)
Flo (7)
ELISA (14)
ICC (1)
IF (2)
IP (5)
Peptide-ELISA (1)
rabbit (29)
mouse (1)
Product Group
IHCPlus (2)
IgG (26)
polyclonal pc (30)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (19)
aa253-281 (7)
N-Terminus (4)
Internal (1)
aa250-300 (1)
aa325-375 (1)
aa425-475 (1)
aa625-675 (1)
No (30)
CCNT1 / Cyclin T1 Antibody - CCNT1 Antibody western blot of mouse testis tissue lysates (35 ug/lane). The CCNT1 antibody detected the CCNT1 protein (arrow).
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CCNT1 / Cyclin T1 Rabbit anti-Human Polyclonal (aa253-281) Antibody
Mouse, Human
Flo, WB
Unconjugated
400 µl/$393
CCNT1 / Cyclin T1 Antibody - Anti-CCNT1 / Cyclin T1 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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CCNT1 / Cyclin T1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
CCNT1 / Cyclin T1 Antibody - CCNT1 / Cyclin T1 antibody Western blot of 721_B Cell lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CCNT1 / Cyclin T1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
CCNT1 / Cyclin T1 Antibody - Anti-CCNT1 / Cyclin T1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:500.
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CCNT1 / Cyclin T1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
50 µl/$515
CCNT1 / Cyclin T1 Antibody - Cyclin T1 was detected in paraffin-embedded sections of mouse intestine tissues using rabbit anti- Cyclin T1 Antigen Affinity purified polyclonal antibody
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CCNT1 / Cyclin T1 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
CCNT1 / Cyclin T1 Antibody - Immunochemical staining of human CCNT1 in human adrenal gland with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.
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CCNT1 / Cyclin T1 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC-P
Unconjugated
100 µl/$412
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CCNT1 / Cyclin T1 Rabbit anti-Human Polyclonal (aa253-281) Antibody
Mouse, Human
ELISA, Flo, WB
Unconjugated
200 µl/$734
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CCNT1 / Cyclin T1 Rabbit anti-Human Polyclonal (aa253-281) (Biotin) Antibody
Mouse, Human
ELISA, Flo, WB
Biotin Conjugated
200 µl/$952
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CCNT1 / Cyclin T1 Rabbit anti-Human Polyclonal (aa253-281) (FITC) Antibody
Mouse, Human
ELISA, Flo, WB
FITC Conjugated
200 µl/$952
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CCNT1 / Cyclin T1 Rabbit anti-Human Polyclonal (aa253-281) (APC) Antibody
Mouse, Human
ELISA, Flo, WB
APC Conjugated
200 µl/$952
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CCNT1 / Cyclin T1 Rabbit anti-Human Polyclonal (aa253-281) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, Flo, WB
HRP Conjugated, Azide-free
200 µl/$952
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CCNT1 / Cyclin T1 Rabbit anti-Human Polyclonal (aa253-281) (PE) Antibody
Mouse, Human
ELISA, Flo, WB
PE Conjugated
200 µl/$952
CCNT1 / Cyclin T1 Antibody - Detection of Human Cyclin T1 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-Cyclin T1 used at a dilution of 1:200 (1 ug/ml). Detection: DAB.
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CCNT1 / Cyclin T1 Rabbit anti-Human Polyclonal (aa250-300) Antibody
Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
CCNT1 / Cyclin T1 Antibody - Detection of Human Cyclin T1 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-Cyclin T1 used at a dilution of 1:200 (1 ug/ml). Detection: DAB.
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CCNT1 / Cyclin T1 Rabbit anti-Human Polyclonal (aa325-375) Antibody
Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
CCNT1 / Cyclin T1 Antibody - Detection of Human Cyclin T1 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-Cyclin T1 used at a dilution of 1:200 (1 ug/ml). Detection: DAB.
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CCNT1 / Cyclin T1 Rabbit anti-Human Polyclonal (aa425-475) Antibody
Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
CCNT1 / Cyclin T1 Antibody - Detection of Human Cyclin T1 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-Cyclin T1 used at a dilution of 1:200 (1 ug/ml). Detection: DAB.
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CCNT1 / Cyclin T1 Rabbit anti-Human Polyclonal (aa625-675) Antibody
Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
CCNT1 / Cyclin T1 Antibody - 1:100 staining human breast carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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CCNT1 / Cyclin T1 Rabbit anti-Human Polyclonal Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CCNT1 / Cyclin T1 Antibody - Immunohistochemistry of paraffin-embedded human thyroid tissue using CCNT1 Antibody at dilution of 1:100
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CCNT1 / Cyclin T1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
50 µg/$294; 100 µg/$360
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CCNT1 / Cyclin T1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
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CCNT1 / Cyclin T1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
CCNT1 / Cyclin T1 Antibody - Western blot analysis of extracts of K562 cell lines.
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CCNT1 / Cyclin T1 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
CCNT1 / Cyclin T1 Antibody - IHC testing of FFPE human intestine cancer tissue with Cyclin T1 antibody at 1ug/ml. HIER: steam in pH6 citrate buffer and allow to cool prior to staining.
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CCNT1 / Cyclin T1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
100 µg/$575
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CCNT1 / Cyclin T1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
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CCNT1 / Cyclin T1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
CCNT1 / Cyclin T1 Antibody - Western blot analysis of extracts of K-562 cells using CCNT1 Polyclonal Antibody.
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CCNT1 / Cyclin T1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).