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CCNL2 / Cyclin L2

cyclin L2

CCNL2 / Cyclin L2 belongs to the cyclin family. Through its interaction with several proteins, such as RNA polymerase II, splicing factors, and cyclin-dependent kinases, this protein functions as a regulator of the pre-mRNA splicing process, as well as in inducing apoptosis by modulating the expression of apoptotic and antiapoptotic proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene Name: cyclin L2
Synonyms: CCNL2, ANIA-6B, CCNM, Cyclin M, HLA-ISO, PCEE, SB138, Cyclin L2, Cyclin-L2, HCLA-ISO
Target Sequences: NM_030937 NP_112199.2 Q96S94

Publications (1)

1
Role of CDK/cyclin complexes in transcription and RNA splicing. Loyer P, Trembley JH, Katona R, Kidd VJ, Lahti JM. Cellular signalling. 2005 17:1033-51. [PubMed:15935619]

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CCNL2 / Cyclin L2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
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58 kDa
20 µg/$215
CCNL2 / Cyclin L2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
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58 kDa
100 µg/$710
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).