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CCNL1 / Cyclin L1

cyclin L1

Cyclin L (also referred to as CCNL) is encoded by two highly related genes Cyclin L1 and Cyclin L2 (CCNL1 and CCNL2, respectively). Cyclin L has been shown to associate with the PITSLRE kinase and is involved in pre-mRNA processing. Both Cyclin L gene products can be alternatively spliced to produce two isoforms (known as 1 and 2 or alpha and beta). Cyclin L2 is ubiquitous, expressed at much higher levels than Cyclin L1, and thus is likely the major partner for the CDK11p110 protein kinase.

Gene Name: cyclin L1
Synonyms: CCNL1, ANIA6A, Ania-6a, BM-001, Cyclin L ania-6a, Cyclin L gamma, Cyclin L1, Cyclin-L, Cyclin-L1, PRO1073
Target Sequences: NM_020307 NP_064703.1 Q9UK58

Publications (1)

1
Role of CDK/cyclin complexes in transcription and RNA splicing. Loyer P, Trembley JH, Katona R, Kidd VJ, Lahti JM. Cellular signalling. 2005 17:1033-51. [PubMed:15935619] Related Antibodies: LS-B80, LS-B79.

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Proteins (3)
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CCNL1 / Cyclin L1 (3)
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HEK 293 Cells (1)
Wheat Germ Extract (1)
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CCNL1 / Cyclin L1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
59.5 kDa
20 µg/$150
CCNL1 / Cyclin L1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
59.5 kDa
100 µg/$494
CCNL1 / Cyclin L1 Protein - 12.5% SDS-PAGE of human CCNL1 stained with Coomassie Blue
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Wheat Germ Extract
GST
44.66 kDa
10 µg/$479; 25 µg/$670
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).