CCNH / Cyclin H

cyclin H

CCNH / Cyclin H belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.

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Products

Proteins (8)

Type

Over-Expression Lysate (2)

Recombinant (6)

Target

CCNH / Cyclin H (8)

Publications

No (8)

Tag

6His, N-terminus (2)

GST (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (3)

Species

Human (7)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (2)

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Human CCNH / Cyclin H Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65321

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.5 kDa

Price:

20 µg/$1,107

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Human CCNH / Cyclin H Protein (Recombinant 6His, N-terminus) (Met1-Leu323) - LS-G39866

Source:

E. coli

Tag:

6His, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

39.8kD

Price:

10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157

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Human CCNH / Cyclin H Protein (Recombinant GST, N-terminus) (aa1-110) - LS-G58021

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human CCNH / Cyclin H Protein (Recombinant GST) (Full Length) - LS-G27780

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

64 kDa

Price:

10 µg/$479; 25 µg/$670

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Human CCNH / Cyclin H Protein (Recombinant 6His, N-terminus) (Met1-Leu323) - LS-G139556

Source:

E. coli

Tag:

6His, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

39.8 kDa

Price:

10 µg/$376; 50 µg/$526

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Human CCNH / Cyclin H Protein (Recombinant His) - LS-G752

Source:

E. coli

Tag:

His

Price:

100 µg/$342; 500 µg/$641; 20 µg/$254

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Human CCNH / Cyclin H Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75347

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.5 kDa

Price:

20 µg/$150

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CCNH / Cyclin H Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118706

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.5 kDa

Price:

100 µg/$494

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