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CCNB1IP1

cyclin B1 interacting protein 1, E3 ubiquitin protein ligase

Ubiquitin E3 ligase that acts as a limiting factor for crossing-over during meiosis: required during zygonema to limit the colocalization of RNF212 with MutS-gamma-associated recombination sites and thereby establish early differentiation of crossover and non-crossover sites. Later, it is directed by MutL-gamma to stably accumulate at designated crossover sites. Probably promotes the dissociation of RNF212 and MutS-gamma to allow the progression of recombination and the implementation of the final steps of crossing over (By similarity). Modulates cyclin-B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis.

Gene Name: cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
Synonyms: CCNB1IP1, C14orf18, HEI10, Human enhancer of invasion 10
Target Sequences: NM_021178 NP_067001.3 Q9NPC3

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Products
Proteins (11)
Over-Expression Lysate (8)
Recombinant (3)
CCNB1IP1 (11)
No (11)
GST (1)
GST, N-terminus (1)
His, N-Terminal (1)
Myc-DDK (Flag) (8)
Human (7)
293T Cells (4)
E. coli (1)
HEK 293 Cells (4)
Wheat Germ Extract (2)
Purified (1)
CCNB1IP1 Protein - 12.5% SDS-PAGE of human CCNB1IP1 stained with Coomassie Blue
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Wheat Germ Extract
GST
57.9 kDa
2 µg/$439
CCNB1IP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
31.4 kDa
20 µg/$150
CCNB1IP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
31.4 kDa
20 µg/$150
CCNB1IP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
31.4 kDa
20 µg/$150
CCNB1IP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
31.4 kDa
20 µg/$150
CCNB1IP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
31.4 kDa
100 µg/$494
CCNB1IP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
31.4 kDa
100 µg/$494
CCNB1IP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
31.4 kDa
100 µg/$494
CCNB1IP1 Protein
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E. coli
His, N-Terminal
31.4 kDa
50 µg/$419
CCNB1IP1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CCNB1IP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
31.4 kDa
100 µg/$494
Viewing 1-11 of 11 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).