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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CCNA1 / Cyclin A1

cyclin A1

CCNA1 / Cyclin A1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: cyclin A1
Synonyms: CCNA1, Cyclin-A1, Cyclin A1
Target Sequences: NM_003914 NP_003905.1 P78396

Filtered By: None
Target
CCNA1 / Cyclin A1 (48)
Reactivity
Human (40)
Mouse (19)
Rat (10)
Bat (1)
Bovine (2)
Chicken (1)
Dog (2)
Guinea pig (1)
Hamster (1)
Horse (1)
Pig (2)
Rabbit (1)
Sheep (1)
Application
IHC (20)
IHC-P (6)
WB (42)
Flo (1)
ELISA (20)
ICC (5)
IF (5)
IP (1)
Peptide-ELISA (1)
Host
rabbit (37)
mouse (11)
Isotype
IgG (28)
IgG1 (1)
IgG1,k (7)
Clonality
monoclonal mc (11)
polyclonal pc (37)
Clone
12K76 (1)
4A11-5B5 (1)
Format
AP Conjugated (2)
APC (1)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (5)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (5)
HRP Conjugated (4)
PE Conjugated (3)
Unconjugated (24)
Epitope
aa183-430 (10)
aa162-188 (8)
380-460 aa, C-terminal (1)
Arg436 (1)
C-Terminus (1)
aa411-460 (1)
aa51-220 (1)
aa64-263 (1)
Publications
No (48)
Showing 1-25 of 48 results

CCNA1 / Cyclin A1 Antibody (aa411-460) IHC-plus™ LS-B7020
Rabbit Polyclonal (IgG) to Human CCNA1 / Cyclin A1
Mouse, Rat, Human
IHC IHC-P Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-CCNA1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Western blot analysis of lysates from SKOV3 cells, using Cyclin A1 Antibody. The lane on the right is blocked with the synthesized peptide.
Anti-CCNA1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Western blot analysis of lysates from SKOV3 cells, using Cyclin A1 Antibody. The lane on the right is blocked with the synthesized peptide.

CCNA1 / Cyclin A1 Antibody (C-Terminus) LS-C354121
Rabbit Polyclonal to Human CCNA1 / Cyclin A1
Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Pig, Human
ICC IF IHC IHC-P WB
Unconjugated
100µl 1mg/ml  $245.00
Immunohistochemical analysis of Cyclin A1 staining in human testis formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of Cyclin A1 staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
Immunohistochemical analysis of Cyclin A1 staining in human testis formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of Cyclin A1 staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).

CCNA1 / Cyclin A1 Antibody LS-C485749
Mouse Monoclonal to Human CCNA1 / Cyclin A1
Human
ELISA ICC IF WB
Unconjugated
50µl  $255.00; 100µl  $305.00; 200µl  $355.00

CCNA1 / Cyclin A1 Antibody LS-C393346
Rabbit Polyclonal to Human CCNA1 / Cyclin A1
Mouse, Rat, Human
IF IHC IHC-P WB
Unconjugated
100µl  $305.00

CCNA1 / Cyclin A1 Antibody LS-C485752
Mouse Monoclonal to Human CCNA1 / Cyclin A1
Human
Flo ICC IF
Unconjugated
50µl  $255.00; 100µl  $305.00; 200µl  $355.00

CCNA1 / Cyclin A1 Antibody LS-C417132
Rabbit Polyclonal to Human CCNA1 / Cyclin A1
Mouse, Human
IF IHC WB
Unconjugated
100µg 1mg/ml  $305.00

CCNA1 / Cyclin A1 Antibody LS-C664902
Rabbit Polyclonal (IgG) to Human CCNA1 / Cyclin A1
Human
ELISA IHC WB
Unconjugated
100µg  $335.00

CCNA1 / Cyclin A1 Antibody (380-460 aa, C-terminal) LS-C382959
Rabbit Polyclonal (IgG) to Human CCNA1 / Cyclin A1
Mouse, Rat, Human
ELISA IHC WB
Unconjugated
100µl 1mg/ml  $265.00
Western blot of Cyclin A1 antibody
Western blot of Cyclin A1 antibody
Western blot of Cyclin A1 antibody
Western blot of Cyclin A1 antibody

CCNA1 / Cyclin A1 Antibody LS-C672018
Rabbit Polyclonal (IgG) to Human CCNA1 / Cyclin A1
Human
ELISA IHC IHC-P
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry image of paraffin-embedded human brain tissue at a dilution of 1:100
Immunohistochemistry image of paraffin-embedded human brain tissue at a dilution of 1:100

CCNA1 / Cyclin A1 Antibody (aa51-220, clone 12K76) LS-C182828
Mouse Monoclonal [clone 12K76] (IgG1) to Human CCNA1 / Cyclin A1
Human
IHC WB
Unconjugated
100µg 200µl 0.5mg/ml  $620.00

CCNA1 / Cyclin A1 Antibody (Arg436) LS-C175984
Rabbit Polyclonal to Human CCNA1 / Cyclin A1
Mouse, Rat, Human
IHC IHC-P WB
Unconjugated
100µl  $345.00
IHC of Cyclin A1 (R436) pAb in paraffin-embedded human breast carcinoma tissue.
Western blot of Cyclin A1 (R436) pAb in extracts from SKOV3 cells treated with Heat shock.
IHC of Cyclin A1 (R436) pAb in paraffin-embedded human breast carcinoma tissue.
Western blot of Cyclin A1 (R436) pAb in extracts from SKOV3 cells treated with Heat shock.

CCNA1 / Cyclin A1 Antibody (aa162-188) LS-C320097
Rabbit Polyclonal (IgG) to Mouse CCNA1 / Cyclin A1
Mouse
ELISA WB
Unconjugated
200µl  $530.00

CCNA1 / Cyclin A1 Antibody (aa162-188, Biotin) LS-C213112
Rabbit Polyclonal (IgG) to Mouse CCNA1 / Cyclin A1
Mouse
ELISA WB
Biotin Conjugated
200µl  $680.00

CCNA1 / Cyclin A1 Antibody (aa162-188, FITC) LS-C213113
Rabbit Polyclonal (IgG) to Mouse CCNA1 / Cyclin A1
Mouse
ELISA WB
FITC Conjugated
200µl  $680.00

CCNA1 / Cyclin A1 Antibody (aa162-188, AP) LS-C213111
Rabbit Polyclonal (IgG) to Mouse CCNA1 / Cyclin A1
Mouse
ELISA WB
AP Conjugated
200µl  $680.00

CCNA1 / Cyclin A1 Antibody (aa162-188, PE) LS-C213114
Rabbit Polyclonal (IgG) to Mouse CCNA1 / Cyclin A1
Mouse
ELISA WB
PE Conjugated
200µl  $680.00

CCNA1 / Cyclin A1 Antibody (aa162-188, Azide-free, HRP) LS-C213115
Rabbit Polyclonal (IgG) to Mouse CCNA1 / Cyclin A1
Mouse
ELISA WB
HRP Conjugated, Azide-free
200µl  $680.00

CCNA1 / Cyclin A1 Antibody (aa162-188, APC) LS-C213110
Rabbit Polyclonal (IgG) to Mouse CCNA1 / Cyclin A1
Mouse
ELISA WB
APC Conjugated
200µl  $680.00

CCNA1 / Cyclin A1 Antibody LS-C485753
Mouse Monoclonal to Human CCNA1 / Cyclin A1
Human
IHC IHC-P
Unconjugated
50µl  $255.00; 100µl  $305.00; 200µl  $355.00

CCNA1 / Cyclin A1 Antibody LS-C485755
Rabbit Polyclonal to Human CCNA1 / Cyclin A1
Human
ELISA IP WB
Unconjugated
50µl  $255.00; 100µl  $305.00; 200µl  $355.00

CCNA1 / Cyclin A1 Antibody (clone 4A11-5B5) LS-C306783
Mouse Monoclonal [clone 4A11-5B5] (IgG1,k) to Human CCNA1 / Cyclin A1
Human
ELISA WB
Unconjugated
100µg  $560.00

CCNA1 / Cyclin A1 Antibody LS-C334178
Rabbit Polyclonal (IgG) to Human CCNA1 / Cyclin A1
Human
IHC WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Western blot analysis of extracts of various cell lines.
Western blot analysis of extracts of various cell lines.

CCNA1 / Cyclin A1 Antibody (aa183-430) LS-C373110
Rabbit Polyclonal (IgG) to Human CCNA1 / Cyclin A1
Human
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $305.00; 1ml 0.5mg/ml  $530.00; 10ml 0.5mg/ml  $2,100.00
Western blot of CCNA1 / Cyclin A1 antibody.
Western blot of CCNA1 / Cyclin A1 antibody.

CCNA1 / Cyclin A1 Antibody LS-C415842
Rabbit Polyclonal to Human CCNA1 / Cyclin A1
Mouse, Rat, Human
IHC WB
Unconjugated
100µg 1mg/ml  $305.00
Western blot of SK-OV3 cell lysate using Cyclin A1 Antibody
Western blot of SK-OV3 cell lysate using Cyclin A1 Antibody

CCNA1 / Cyclin A1 Antibody LS-C136874
Rabbit Polyclonal (IgG) to Human CCNA1 / Cyclin A1
Mouse, Rat, Human
ELISA WB
Unconjugated
100µl  $255.00
Western blot Image
Western blot Image
Showing 1-25 of 48 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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