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Unfortunately, the antibody (ID:167339) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



CCM1 / KRIT1

KRIT1, ankyrin repeat containing

Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity (By similarity). Negative regulator of angiogenesis. Inhibits endothelial proliferation, apoptosis, migration, lumen formation and sprouting angiogenesis in primary endothelial cells. Promotes AKT phosphorylation in a NOTCH-dependent and independent manner, and inhibits ERK1/2 phosphorylation indirectly through activation of the DELTA-NOTCH cascade. Acts in concert with CDH5 to establish and maintain correct endothelial cell polarity and vascular lumen and these effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction, and cell junction stabilization. Plays a role in integrin signaling via its interaction with ITGB1BP1; this prevents the interaction between ITGB1 and ITGB1BP1. Microtubule-associated protein that binds to phosphatidylinositol 4,5-bisphosphate (PIP2)-containing membranes in a GTP-bound RAP1-dependent manner. Plays an important role in the maintenance of the intracellular reactive oxygen species (ROS) homeostasis to prevent oxidative cellular damage. Regulates the homeostasis of intracellular ROS through an antioxidant pathway involving FOXO1 and SOD2. Facilitates the down-regulation of cyclin-D1 (CCND1) levels required for cell transition from proliferative growth to quiescence by preventing the accumulation of intracellular ROS through the modulation of FOXO1 and SOD2 levels.

Gene Name: KRIT1, ankyrin repeat containing
Synonyms: KRIT1, CaM, CCM1, Krev interaction trapped 1
Target Sequences: NM_004912 NP_004903.2 O00522

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Target Reactivity Applications Host Isotype Clonality Clone Format Epitope Publications Type
CCM1 / KRIT1 Mouse IgG2a,l Monoclonal 2C7 Unconjugated Human ELISA No Primary
Anti-CCM1 / KRIT1 Antibody (clone 2C7) LS-C196831
Enzyme-Linked Immunosorbent Assay Image
Mouse Monoclonal [clone 2C7] (IgG2a,l) to Human CCM1 / KRIT1
Human
ELISA
Unconjugated
CCM1 / KRIT1 Rabbit Polyclonal Unconjugated Human WB aa6-34 No Primary
Anti-CCM1 / KRIT1 Antibody (aa6-34) LS-C160019
Western blot Image
Rabbit Polyclonal to Human CCM1 / KRIT1
Human
Western blot
Unconjugated
CCM1 / KRIT1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IF, WB No Primary
Anti-CCM1 / KRIT1 Antibody LS-C346127
Rabbit Polyclonal (IgG) to Human CCM1 / KRIT1
Human, Mouse, Rat
Immunofluorescence, Western blot
Unconjugated
CCM1 / KRIT1 Mouse IgG2a Monoclonal PE Conjugated Human WB, ELISA aa637-737 No Primary
Anti-CCM1 / KRIT1 Antibody (aa637-737, PE) LS-C244896
Mouse Monoclonal (IgG2a) to Human CCM1 / KRIT1
Human
Western blot, ELISA
PE Conjugated
CCM1 / KRIT1 Mouse IgG2a Monoclonal FITC Conjugated Human WB, ELISA aa637-737 No Primary
Anti-CCM1 / KRIT1 Antibody (aa637-737, FITC) LS-C244895
Mouse Monoclonal (IgG2a) to Human CCM1 / KRIT1
Human
Western blot, ELISA
FITC Conjugated
CCM1 / KRIT1 Mouse IgG2a Monoclonal Biotin Conjugated Human WB, ELISA aa637-737 No Primary
Anti-CCM1 / KRIT1 Antibody (aa637-737, Biotin) LS-C244894
Mouse Monoclonal (IgG2a) to Human CCM1 / KRIT1
Human
Western blot, ELISA
Biotin Conjugated
CCM1 / KRIT1 Mouse IgG2a Monoclonal HRP Conjugated, Azide-free Human WB, ELISA aa637-737 No Primary
Anti-CCM1 / KRIT1 Antibody (aa637-737, Azide-free, HRP) LS-C247676
Mouse Monoclonal (IgG2a) to Human CCM1 / KRIT1
Human
Western blot, ELISA
HRP Conjugated, Azide-free
CCM1 / KRIT1 Mouse IgG2a Monoclonal Unconjugated, Azide-free Human WB, ELISA aa637-737 No Primary
Anti-CCM1 / KRIT1 Antibody (aa637-737, Azide-free) LS-C327732
Mouse Monoclonal (IgG2a) to Human CCM1 / KRIT1
Human
Western blot, ELISA
Unconjugated, Azide-free
CCM1 / KRIT1 Rabbit IgG Polyclonal Unconjugated Human WB, ELISA aa5-34 No Primary
Anti-CCM1 / KRIT1 Antibody (aa5-34) LS-C322549
Rabbit Polyclonal (IgG) to Human CCM1 / KRIT1
Human
Western blot, ELISA
Unconjugated
CCM1 / KRIT1 Rabbit IgG Polyclonal HRP Conjugated, Azide-free Human WB, ELISA aa6-34 No Primary
Anti-CCM1 / KRIT1 Antibody (aa6-34, Azide-free, HRP) LS-C248668
Rabbit Polyclonal (IgG) to Human CCM1 / KRIT1
Human
Western blot, ELISA
HRP Conjugated, Azide-free
CCM1 / KRIT1 Rabbit IgG Polyclonal FITC Conjugated Human WB, ELISA aa6-34 No Primary
Anti-CCM1 / KRIT1 Antibody (aa6-34, FITC) LS-C236927
Rabbit Polyclonal (IgG) to Human CCM1 / KRIT1
Human
Western blot, ELISA
FITC Conjugated
CCM1 / KRIT1 Rabbit IgG Polyclonal Biotin Conjugated Human WB, ELISA aa6-34 No Primary
Anti-CCM1 / KRIT1 Antibody (aa6-34, Biotin) LS-C236926
Rabbit Polyclonal (IgG) to Human CCM1 / KRIT1
Human
Western blot, ELISA
Biotin Conjugated
CCM1 / KRIT1 Rabbit IgG Polyclonal AP Conjugated Human WB, ELISA aa6-34 No Primary
Anti-CCM1 / KRIT1 Antibody (aa6-34, AP) LS-C236925
Rabbit Polyclonal (IgG) to Human CCM1 / KRIT1
Human
Western blot, ELISA
AP Conjugated
CCM1 / KRIT1 Rabbit IgG Polyclonal APC Conjugated Human WB, ELISA aa6-34 No Primary
Anti-CCM1 / KRIT1 Antibody (aa6-34, APC) LS-C236928
Rabbit Polyclonal (IgG) to Human CCM1 / KRIT1
Human
Western blot, ELISA
APC Conjugated
CCM1 / KRIT1 Mouse IgG2a Monoclonal APC Conjugated Human WB, ELISA aa637-737 No Primary
Anti-CCM1 / KRIT1 Antibody (aa637-737, APC) LS-C244892
Mouse Monoclonal (IgG2a) to Human CCM1 / KRIT1
Human
Western blot, ELISA
APC Conjugated
CCM1 / KRIT1 Mouse IgG2a Monoclonal AP Conjugated Human WB, ELISA aa637-737 No Primary
Anti-CCM1 / KRIT1 Antibody (aa637-737, AP) LS-C244891
Mouse Monoclonal (IgG2a) to Human CCM1 / KRIT1
Human
Western blot, ELISA
AP Conjugated
CCM1 / KRIT1 Rabbit IgG Polyclonal PE Conjugated Human WB, ELISA aa6-34 No Primary
Anti-CCM1 / KRIT1 Antibody (aa6-34, PE) LS-C236929
Rabbit Polyclonal (IgG) to Human CCM1 / KRIT1
Human
Western blot, ELISA
PE Conjugated
Target Corresponding Antibodies
CCM1 / KRIT1
CCM1 / KRIT1 Antibody Blocking Peptide - LS-E5671
LS-E5671
CCM1 / KRIT1
LS-C160019
Type Target Tag Species Source Purified Biological Activity Known Endotoxin Level Animal-Free
Recombinant CCM1 / KRIT1 GST Human Wheat
Human CCM1 / KRIT1 Recombinant (GST) Protein - LS-G27771
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Wheat Wheat Germ Extract
GST
Unpurified / Lyophilized

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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