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CCL8 / MCP2

chemokine (C-C motif) ligand 8

This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.

Gene Name: chemokine (C-C motif) ligand 8
Family/Subfamily: Intercrine , Intercrine beta
Synonyms: CCL8, C-C motif chemokine 8, HC14, MCP2, Monocyte chemotactic protein 2, Scya10, SCYA8, Small-inducible cytokine A8, MCP-2, Chemokine (C-C motif) ligand 8
Target Sequences: NM_005623 NP_005614.2 P80075

Publications (1)

1
Iron accelerates Fusobacterium nucleatum-induced CCL8 expression in macrophages and is associated with colorectal cancer progression. Taishi Yamane, Yohei Kanamori, Hiroshi Sawayama, Hiromu Yano, Akihiro Nita, Yudai Ohta, Hironori Hinokuma, Ayato Maeda, Akiko Iwai, Takashi Matsumoto, Mayuko Shimoda, Mayumi Niimura, Shingo Usuki, Noriko Yasuda-Yoshihara, Masato Niwa, Yoshifumi Baba, Takatsugu Ishimoto, Yoshihiro Komohara, Tomohiro Sawa, Tasuku Hirayama, Hideo Baba, Toshiro Moroishi. JCI insight. 2022 November;7: [Full Text Article] [PubMed:36136589] [PMC:PMC9675438] Related Antibodies: LS-B8198.

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Products
Antibodies (60)
Primary (60)
CCL8 / MCP2 (60)
Human (28)
Mouse (16)
Bovine (8)
Cow (8)
Gibbon (3)
Monkey (3)
Pig (8)
IHC (9)
IHC-P (9)
WB (54)
ELISA (21)
Peptide-ELISA (1)
rabbit (59)
mouse (1)
Product Group
IHCPlus (2)
IgG (21)
IgG1,k (1)
monoclonal mc (1)
polyclonal pc (59)
APC (4)
APC Conjugated (4)
Biotin Conjugated (10)
Cy3 Conjugated (4)
Cy7 Conjugated (4)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (4)
Preservative Free (3)
Unconjugated (22)
aa1-99 (16)
aa20-94 (8)
aa24-99 (8)
C-Terminus (4)
41-90 aa, C-terminal (1)
aa23-99 (1)
No (59)
Yes (1)
CCL8 / MCP2 Antibody - Anti-MCP-2 / CCL8 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.
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CCL8 / MCP2 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
500 µg/$460
CCL8 / MCP2 Antibody - Western Blot (non-reducing) of MCP-2 / CCL8 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CCL8 / MCP2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
CCL8 / MCP2 Antibody - Western Blot (non-reducing) of MCP-2 / CCL8 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CCL8 / MCP2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
25 µg/$356; 50 µg/$396
CCL8 / MCP2 Antibody - IHC staining of FFPE mouse spleen with Mcp2 antibody at 1ug/ml. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min followed by cooling at RT for 20 min.
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CCL8 / MCP2 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, IHC-P
Unconjugated
100 µg/$575
CCL8 / MCP2 Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CCL8 / MCP2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
CCL8 / MCP2 Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CCL8 / MCP2 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Human, Monkey, Gibbon
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
CCL8 / MCP2 Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CCL8 / MCP2 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Human, Monkey, Gibbon
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
CCL8 / MCP2 Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CCL8 / MCP2 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Human, Monkey, Gibbon
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
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CCL8 / MCP2 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, IHC, IHC-P
Unconjugated
100 µl/$412
CCL8 / MCP2 Antibody - Anti-Murine MCP-2 (CCL8) Western Blot Reduced
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CCL8 / MCP2 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
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CCL8 / MCP2 Rabbit anti-Mouse Polyclonal (Biotin) Antibody
Mouse
ELISA, WB
Biotin Conjugated
25 µg/$356; 50 µg/$396
CCL8 / MCP2 Antibody - Immunohistochemistry of paraffin-embedded human small intestine using antibody at 1:100 dilution.
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CCL8 / MCP2 Rabbit anti-Human Polyclonal (aa23-99) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
CCL8 / MCP2 Antibody - IHC analysis of CCL8 using anti-CCL8 antibody. CCL8 was detected in paraffin-embedded section of mouse kidney tissue. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 2µg/ml rabbit anti-CCL8 Antibody overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
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CCL8 / MCP2 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, IHC-P
Unconjugated
10 µg/$318; 100 µg/$470
CCL8 / MCP2 Antibody - Immunohistochemistry of paraffin-embedded human liver tissue.
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CCL8 / MCP2 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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CCL8 / MCP2 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
50 µg/$785
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CCL8 / MCP2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
500 µg/$2,497
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CCL8 / MCP2 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA, WB
Unconjugated, Preservative Free
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
CCL8 / MCP2 Antibody - Western blot analysis of lysate from L929 cells, using CCL8 Antibody.
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CCL8 / MCP2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CCL8 / MCP2 Antibody - Western blot of MCP-2 antibody
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CCL8 / MCP2 Rabbit anti-Human Polyclonal (41-90 aa, C-terminal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CCL8 / MCP2 Antibody - Immunohistochemistry of paraffin-embedded human gastric cancer using CCL8 Antibody at dilution of 1:100
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CCL8 / MCP2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
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CCL8 / MCP2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
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CCL8 / MCP2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
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CCL8 / MCP2 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
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CCL8 / MCP2 Rabbit anti-Mouse Polyclonal (Biotin) Antibody
Mouse
ELISA, WB
Biotin Conjugated
50 µg/$563
CCL8 / MCP2 Antibody - Western blot analysis of extracts of Fetal heart lysate using CCL8 antibody. The lane on the left was treated with blocking peptide.
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CCL8 / MCP2 Rabbit anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Viewing 1-25 of 60 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).