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CCL7 / MCP3

chemokine (C-C motif) ligand 7

CCL7 / MCP3 is monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q.

Gene Name: chemokine (C-C motif) ligand 7
Family/Subfamily: Intercrine , Intercrine beta
Synonyms: CCL7, C-C motif chemokine 7, Chemokine (C-C motif) ligand 7, FIC, MARC, MCP3, Monocyte chemotactic protein 3, SCYA7, Small-inducible cytokine A7, MCP-3, SCYA6, NC28
Target Sequences: NM_006273 NP_006264.2 P80098

Publications (1)

1
An initial investigation into endothelial CC chemokine expression in the human rheumatoid synovium. Rump L, Mattey DL, Kehoe O, Middleton J. Cytokine. 2017 September;97:133-140. (Human) [Full Text Article] [PubMed:28648867] [PMC:PMC5516773] Related Antibodies: LS-B930.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).