Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
CCL27 is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation.
|Gene Name:||chemokine (C-C motif) ligand 27|
|Family/Subfamily:||Intercrine , Intercrine beta|
|Synonyms:||CCL27, ALP, Chemokine alp, C-C motif chemokine 27, CC chemokine ILC, CTAK, ESKINE, IL-11 R-alpha-locus chemokine, ILC, IL-11 Ralpha-locus chemokine, PESKY, SCYA27, Skinkine, CTACK, Il-11r alpha-locus chemokine, Small-inducible cytokine A27|
|Target Sequences:||NM_006664 NP_006655.1 Q9Y4X3|
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