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CCL25 / TECK

chemokine (C-C motif) ligand 25

Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.

Gene Name:	chemokine (C-C motif) ligand 25
Family/Subfamily:	Intercrine , Intercrine beta
Synonyms:	CCL25, C-C motif chemokine 25, Ck beta-15, TECK, Thymus-expressed chemokine, Small-inducible cytokine A25, TECKvar, Chemokine TECK, Ckb15, SCYA25, Thymus expressed chemokine
Target Sequences:	NM_005624 NP_005615.2 O15444

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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