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CCL22 / MDC

chemokine (C-C motif) ligand 22

This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology.

Gene Name: chemokine (C-C motif) ligand 22
Family/Subfamily: Intercrine , Intercrine beta
Synonyms: CCL22, A-152E5.1, ABCD-1, CC chemokine STCP-1, DC/B-CK, Macrophage-derived chemokine, MDC(1-69), MDC, SCYA22, Small inducible cytokine A22, STCP-1, C-C motif chemokine 22, Small-inducible cytokine A22
Target Sequences: NM_002990 NP_002981.2 O00626

☰ Filters
Products
Proteins (24)
Over-Expression Lysate (2)
Recombinant (22)
CCL22 / MDC (24)
No (24)
GST (2)
His (3)
His-GST (4)
Human IgG1 Fc (1)
Mouse IgG2 Fc (1)
Myc-DDK (Flag) (3)
Bovine (1)
Dog (1)
Human (14)
Mouse (5)
Rat (2)
293T Cells (1)
CHO Cells (2)
E. coli (18)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (12)
Low endotoxin level (9)
Biologically active (10)
CCL22 / MDC Protein - Purified recombinant protein CCL22 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
8 kDa
20 µg/$1,107
CCL22 / MDC Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
10.58 kDa
20 µg/$150
Select
E. coli
His
9.7 kDa
50 µg/$520; 1 mg/$3,773
CCL22 / MDC Protein - Baf3-hCCR4 transfectants attracted by human CCL22.
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg (determined by LAL method).
The 69 amino acid recombinant protein has a predicted molecular mass of approximately 8 kD. The DTT-reduced protein migrates at approximately 10 kD and non-reduced protein migrates at 11 kD by SDS-PAGE. The N-terminal amino acid is Glycine.
10 µg/$306; 25 µg/$375
Select
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
~8 kDa
20 µg/$432; 1 mg/$4,915
CCL22 / MDC Protein
Select
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
~8 kDa
20 µg/$376; 100 µg/$1,353; 1 mg/$4,915
CCL22 / MDC Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
10.58 kDa
100 µg/$494
Select
CHO Cells
Human IgG1 Fc
Less than 0.06 EU/µg protein (determined by LAL method).
50 µg/$386
CCL22 / MDC Protein - Recombinant Macrophage Derived Chemokine By SDS-PAGE
Select
E. coli
His-GST
43.0 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
CCL22 / MDC Protein - Recombinant Macrophage Derived Chemokine By SDS-PAGE
Select
E. coli
His-GST
43.0 kDa
10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334
CCL22 / MDC Protein - Recombinant Macrophage Derived Chemokine By SDS-PAGE
Select
E. coli
His-GST
40.5 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
CCL22 / MDC Protein - Recombinant Macrophage Derived Chemokine By SDS-PAGE
Select
E. coli
His
9.0 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
CCL22 / MDC Protein - Recombinant Macrophage Derived Chemokine By SDS-PAGE
Select
E. coli
His-GST
40.2 kDa
10 µg/$281; 50 µg/$442; 100 µg/$707; 200 µg/$885; 1 mg/$1,994; 500 µg/$1,534; 5 mg/$3,095; 2 mg/$2,181
Select
CHO Cells
Mouse IgG2 Fc
Less than 0.06 EU/µg protein (determined by LAL method).
50 µg/$393
Select
E. coli
None
Biologically active
8.1 kDa
20 µg/$377
CCL22 / MDC Protein
Select
E. coli
None
Biologically active
8.1 kDa
5 µg/$282; 100 µg/$957; 500 µg/$1,747
CCL22 / MDC Protein
Select
E. coli
None
Biologically active
7.8 kDa
5 µg/$282; 100 µg/$1,116; 500 µg/$2,095
CCL22 / MDC Protein
Select
E. coli
None
Biologically active
7.9 kDa
5 µg/$282; 100 µg/$1,116; 500 µg/$2,095
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
8.1 kDa
5 µg/$268; 20 µg/$349
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
8.0 kDa
5 µg/$268; 20 µg/$349
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
7.8 kDa
5 µg/$268; 20 µg/$349
CCL22 / MDC Protein
Select
E. coli
His
Less than 1.0 EU/µg protein (determined by LAL method).
100 µg/$317; 500 µg/$526; 20 µg/$245
CCL22 / MDC Protein - 12.5% SDS-PAGE of human CCL22 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
35.97 kDa
10 µg/$479; 25 µg/$670
Select
E. coli
GST
34.1 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Viewing 1-24 of 24 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).