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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CCL21 / SLC

chemokine (C-C motif) ligand 21

This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).

Gene Name: chemokine (C-C motif) ligand 21
Family/Subfamily: Intercrine , Intercrine beta
Synonyms: CCL21, 6Ckine, Beta chemokine exodus-2, C-C motif chemokine 21, Beta-chemokine exodus-2, CKb9, ECL, Small-inducible cytokine A21, SCYA21, SLC, Exodus-2, TCA4
Target Sequences: NM_002989 NP_002980.1 O00585

Publications (2)

1
Integrated pharmacokinetic, pharmacodynamic and immunogenicity profiling of an anti-CCL21 monoclonal antibody in cynomolgus monkeys. Dudal S, Subramanian K, Flandre T, Law WS, Lowe PJ, Skerjanec A, Genin JC, Duval M, Piequet A, Cordier A, Jarai G, Van Heeke G, Taplin S, Krantz C, Jones S, Warren AP, Brennan FR, Sims J, Lloyd P. mAbs. 2015 7:829-37. (WB; Human) [Full Text Article] [PubMed:26230385] [PMC:PMC4622749] Related Antibodies: LS-C104622.
2
Renal allograft rejection, lymphocyte infiltration, and de novo donor-specific antibodies in a novel model of non-adherence to immunosuppressive therapy. Kühne L, Jung B, Poth H, Schuster A, Wurm S, Ruemmele P, Banas B, Bergler T. BMC immunology. 2017 December;18:52. (Mouse) [Full Text Article] [PubMed:29258420] [PMC:PMC5735914]

Viewing 1-25 of 89 items
CCL21 / SLC Antibody - Western Blot (non-reducing) of SLC / CCL21 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Mouse CCL21 / SLC
Mouse
ELISA, WB
Unconjugated
50µg   $285.00; 100µg   $325.00
CCL21 / SLC Antibody - Western Blot (non-reducing) of SLC / CCL21 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Mouse CCL21 / SLC
Mouse
ELISA, WB
Biotin Conjugated
25µg   $285.00; 50µg   $325.00
CCL21 / SLC Antibody - CCL21 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded mouse heart tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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Rabbit Polyclonal to Human CCL21 / SLC
Human
IHC, IHC-P, WB
Unconjugated
400µl   $325.00
CCL21 / SLC Antibody - Western Blot (non-reducing) of SLC / CCL21 antibody
Select
Rabbit Polyclonal (IgG) to Human CCL21 / SLC
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µg   $285.00; 100µg   $325.00
CCL21 / SLC Antibody - Biotinylated Anti-Human Exodus-2 (CCL21) Western Blot Unreduced
Select
(1) Publication(s)
Rabbit Polyclonal to Human CCL21 / SLC
Human
ELISA, WB
Biotin Conjugated
25µg   $285.00; 50µg   $325.00
Select
Rabbit Polyclonal to Rat CCL21 / SLC
Rat
WB
Unconjugated
100µg   $455.00
Select
Rabbit Polyclonal (IgG) to Human CCL21 / SLC
Human
ELISA, IHC, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human CCL21 / SLC
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human CCL21 / SLC
Human
ELISA, IHC, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human CCL21 / SLC
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human CCL21 / SLC
Human
ELISA, IHC, WB
PE Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human CCL21 / SLC
Human
ELISA, IHC, WB
APC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human CCL21 / SLC
Human
ELISA, IHC, WB
AP Conjugated
200µl   $740.00
CCL21 / SLC Antibody
Select
Rabbit Polyclonal to Human CCL21 / SLC
Human
IHC, IHC-P, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $275.00
Select
Rabbit Polyclonal (IgG) to Human CCL21 / SLC
Human
ELISA, WB
Unconjugated
50µg   3mg/ml   $285.00; 100µg   $385.00
CCL21 / SLC Antibody
Select
Rabbit Polyclonal to Human CCL21 / SLC
Human
WB
Unconjugated
100µl   0.5mg/ml   $255.00
Select
Rabbit Polyclonal to Rat CCL21 / SLC
Rat
WB
Unconjugated
100µg   200µl   $395.00
CCL21 / SLC Antibody - Western blot of recombinant CCL21 / Exodus 2 / SLC.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Rat CCL21 / SLC
Rat
WB
Unconjugated
20µl   0.5mg/ml   $205.00; 100µl   0.5mg/ml   $265.00; 200µl   0.5mg/ml   $305.00; 1ml   0.5mg/ml   $545.00
CCL21 / SLC Antibody - Immunohistochemical analysis of paraffin-embedded human-lymph, antibody was diluted at 1:200.
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Rabbit Polyclonal (IgG) to Human CCL21 / SLC
Human
ELISA, IHC
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
CCL21 / SLC Antibody
Select
Rabbit Polyclonal (IgG) to Human CCL21 / SLC
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
CCL21 / SLC Antibody - Immunohistochemistry of paraffin-embedded human liver tissue.
Select
Rabbit Polyclonal (IgG) to Human CCL21 / SLC
Human
IHC, WB
Unconjugated
50µl   $235.00; 100µl   $315.00; 200µl   $425.00
Select
Rabbit Polyclonal (IgG) to Human CCL21 / SLC
Human
ELISA, IHC
Unconjugated
50µg   1mg/ml   $265.00; 100µg   1mg/ml   $325.00
CCL21 / SLC Antibody - Immunohistochemistry of paraffin-embedded Human cervical cancer using CCL21 Polyclonal Antibody at dilution of 1:40.
Select
Rabbit Polyclonal (IgG) to Human CCL21 / SLC
Human
ELISA, IHC
Unconjugated
20µl   0.5mg/ml   $205.00; 60µl   0.5mg/ml   $235.00; 120µl   0.5mg/ml   $295.00; 200µl   0.5mg/ml   $395.00
Select
Rabbit Polyclonal to Human CCL21 / SLC
Human
IHC, WB
Unconjugated
100µl   1mg/ml   $385.00
CCL21 / SLC Antibody - Immunohistochemistry of paraffin-embedded Human colon cancer using CCL21 Polyclonal Antibody at dilution of 1:40.
Select
Rabbit Polyclonal (IgG) to Human CCL21 / SLC
Human
ELISA, IHC
Unconjugated
20µl   0.6mg/ml   $205.00; 60µl   0.6mg/ml   $235.00; 120µl   0.6mg/ml   $295.00; 200µl   0.6mg/ml   $395.00

Viewing 1-25 of 89 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).