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CCL20 / MIP-3-Alpha

chemokine (C-C motif) ligand 20

Chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli ATCC 25922 and S.aureus ATCC 29213.

Gene Name: chemokine (C-C motif) ligand 20
Family/Subfamily: Intercrine , Intercrine beta
Synonyms: CCL20, Beta chemokine exodus-1, Beta-chemokine exodus-1, CKb4, Exodus-1, MIP-3a, MIP-3-alpha, LARC, ST38, SCYA20, C-C motif chemokine 20, CC chemokine LARC, Mip-3alpha, MIP3A, Small-inducible cytokine A20
Target Sequences: NM_004591 NP_004582.1 P78556

Publications (1)

1
Immunotopographical Differences of Human Skin. Béke G, Dajnoki Z, Kapitány A, Gáspár K, Medgyesi B, Póliska S, Hendrik Z, Péter Z, Törocsik D, Bíró T, Szegedi A. Frontiers in immunology. 2018 March;9:424. (Human) [Full Text Article] [PubMed:29556238] [PMC:PMC5844973] Related Antibodies: LS-B7409.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).