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Shirley, MA 01464
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20700 44th Avenue W
Lynnwood, WA 98036
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CCL19 / MIP3-Beta
chemokine (C-C motif) ligand 19
May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
| Gene Name: | chemokine (C-C motif) ligand 19 |
| Family/Subfamily: | Intercrine , Intercrine beta |
| Synonyms: | CCL19, C-C motif chemokine 19, CKb11, CC chemokine ligand 19, EBI1 ligand chemokine, EBI1-ligand chemokine, Exodus-3, ELC, MIP-3-beta, MIP3B, SCYA19, Small-inducible cytokine A19, Beta chemokine exodus-3, Beta-chemokine exodus-3, CK beta-11, MIP-3b |
| Target Sequences: | NM_006274 NP_006265.1 Q99731 |
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