Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
|Gene Name:||chemokine (C-C motif) ligand 19|
|Family/Subfamily:||Intercrine , Intercrine beta|
|Synonyms:||CCL19, C-C motif chemokine 19, CKb11, CC chemokine ligand 19, EBI1 ligand chemokine, EBI1-ligand chemokine, Exodus-3, ELC, MIP-3-beta, MIP3B, SCYA19, Small-inducible cytokine A19, Beta chemokine exodus-3, Beta-chemokine exodus-3, CK beta-11, MIP-3b|
|Target Sequences:||NM_006274 NP_006265.1 Q99731|
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