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CCL17 / TARC

chemokine (C-C motif) ligand 17

This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.

Gene Name: chemokine (C-C motif) ligand 17
Family/Subfamily: Intercrine , Intercrine beta
Synonyms: CCL17, A-152E5.3, C-C motif chemokine 17, CC chemokine abcd-2, ABCD-2, SCYA17, T cell-directed CC chemokine, TARC, CC chemokine TARC, Small-inducible cytokine A17
Target Sequences: NM_002987 NP_002978.1 Q92583

Publications (1)

1
Cancer associated fibroblasts (CAFs) are activated in cutaneous basal cell carcinoma and in the peritumoural skin. Omland SH, Wettergren EE, Mollerup S, Asplund M, Mourier T, Hansen AJ, Gniadecki R. BMC cancer. 2017 17:675. (IHC, ELISA; Human) [Full Text Article] [PubMed:28987144] [PMC:PMC5806272] Related Antibodies: LS-C198166.

☰ Filters
Products
Proteins (18)
Over-Expression Lysate (2)
Recombinant (16)
CCL17 / TARC (18)
No (18)
GST, N-terminus (1)
His (5)
His, C-Terminal (1)
His,C-terminus (1)
Myc-DDK (Flag) (2)
Human (12)
Mouse (3)
Rat (2)
293T Cells (1)
E. coli (13)
HEK 293 Cells (1)
Human (1)
Mammalian Cells (1)
Wheat Germ Extract (1)
Purified (7)
Low endotoxin level (8)
Biologically active (8)
CCL17 / TARC Protein - Recombinant Thymus Activation Regulated Chemokine By SDS-PAGE
Select
E. coli
His
9.6 kDa
10 µg/$283; 50 µg/$452; 100 µg/$725; 200 µg/$905; 1 mg/$2,020; 500 µg/$1,558; 5 mg/$3,165; 2 mg/$2,209
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
8.0 kDa
5 µg/$268; 20 µg/$349
Select
Human
His, C-Terminal
Less than 1.0 EU/µg protein (determined by LAL method).
9.1kD
10 µg/$266; 50 µg/$376; 500 µg/$1,067; 1 mg/$1,369
CCL17 / TARC Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CCL17 / TARC Protein - Recombinant Thymus Activation Regulated Chemokine By SDS-PAGE
Select
E. coli
His
9.3 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
CCL17 / TARC Protein - Recombinant Thymus Activation Regulated Chemokine By SDS-PAGE
Select
E. coli
His
9.3 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
Select
E. coli
His
9.3 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
CCL17 / TARC Protein - Mouse CCL17 chemoattracts BaF3-hCCR4 transfectants.
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg (determined by LAL method).
The 71 amino acid recombinant protein has a predicted molecular mass of approximately 7.98 kD. The DTT-reduced protein migrates at approximately 12 kD and non-reduced protein at approximately 14 kD by SDS-PAGE. The N-terminal amino acid is Ala.
10 µg/$291; 25 µg/$375; 100 µg/$782
CCL17 / TARC Protein - BaF3-hCCR4 transfectants chemoattracted by human CCL17.
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg (determined by LAL method).
The 71 amino acid recombinant protein has a predicted molecular mass of approximately 8 kD. The DTT-reduced protein migrates at approximately 10 kD and non-reduced protein migrates at approximately 11 kD by SDS-PAGE. The N-terminal amino acid is Ala.
10 µg/$283; 25 µg/$359; 100 µg/$744
Select
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
9.1 kDa
10 µg/$266; 50 µg/$371
Select
E. coli
None
Biologically active
Less than 1 EU/µg (determined by LAL method).
8.1 kDa
1 mg/$2,880; 20 µg/$372
Select
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
~8 kDa
20 µg/$381; 1 mg/$3,781
CCL17 / TARC Protein
Select
E. coli
His
Less than 1.0 EU/µg protein (determined by LAL method).
50 µg/$361; 250 µg/$739; 10 µg/$261
CCL17 / TARC Protein
Select
E. coli
None
Biologically active
8.1 kDa
5 µg/$282; 100 µg/$957; 500 µg/$1,747
CCL17 / TARC Protein
Select
E. coli
None
Biologically active
7.9 kDa
5 µg/$282; 100 µg/$1,116; 500 µg/$2,095
CCL17 / TARC Protein
Select
E. coli
None
Biologically active
8.1 kDa
5 µg/$282; 100 µg/$1,116; 500 µg/$2,095
CCL17 / TARC Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
10.51 kDa
20 µg/$150
CCL17 / TARC Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
10.51 kDa
100 µg/$494
Viewing 1-18 of 18 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).