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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CCDC88A / GIV / Girdin

coiled-coil domain containing 88A

Plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Enhances phosphoinositide 3-kinase (PI3K)-dependent phosphorylation and kinase activity of AKT1/PKB, but does not possess kinase activity itself. Phosphorylation of AKT1/PKB thereby induces the phosphorylation of downstream effectors GSK3 and FOXO1/FKHR, and regulates DNA replication and cell proliferation (By similarity). Essential for the integrity of the actin cytoskeleton and for cell migration. Required for formation of actin stress fibers and lamellipodia. May be involved in membrane sorting in the early endosome.

Gene Name: coiled-coil domain containing 88A
Synonyms: CCDC88A, AKT-phosphorylation enhancer, APE, Akt phosphorylation enhancer, GIV, Girders of actin filament, Girdin, GRDN, Hook-related protein 1, KIAA1212, HkRP1
Target Sequences: NM_001135597 NP_001129069.1 Q3V6T2

Filtered by: None
Target
CCDC88A / GIV / Girdin (10)
Reactivity
Human (10)
Mouse (7)
Rat (2)
Application
IHC (9)
IHC-P (4)
WB (4)
ELISA (4)
IF (1)
IP (2)
Peptide-ELISA (2)
Host
rabbit (10)
Isotype
IgG (9)
Clonality
polyclonal pc (10)
Format
Unconjugated (10)
Epitope
1360-1440 aa (2)
aa1383-1432 (1)
aa1425-1475 (1)
aa425-475 (1)
pSer1417 (1)
Publications
No (10)
Showing 1-10 of 10 results

CCDC88A / GIV / Girdin Antibody IHC-plus™ LS-B5063
Rabbit Polyclonal (IgG) to Human CCDC88A / GIV / Girdin
Mouse, Rat, Human
ELISA IF IHC IHC-P WB
Unconjugated
0.05mg 1mg/ml  $425.00
Anti-Girdin antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Immunofluorescence of Girdin in cells with Girdin antibody at 20 ug/ml.

CCDC88A / GIV / Girdin Antibody (aa1425-1475) IHC-plus™ LS-B15080
Rabbit Polyclonal (IgG) to Human CCDC88A / GIV / Girdin
Human
IHC IHC-P IP WB
Unconjugated
50µl 1mg/ml  $425.00
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

CCDC88A / GIV / Girdin Antibody (1360-1440 aa) LS-C381680
Rabbit Polyclonal (IgG) to Human CCDC88A / GIV / Girdin
Mouse, Human
ELISA IHC
Unconjugated
100µl 1mg/ml  $265.00

CCDC88A / GIV / Girdin Antibody (1360-1440 aa) LS-C383693
Rabbit Polyclonal (IgG) to Human CCDC88A / GIV / Girdin
Mouse, Human
ELISA IHC
Unconjugated
100µl 1mg/ml  $265.00

CCDC88A / GIV / Girdin Antibody LS-C193976
Rabbit Polyclonal (IgG) to Human CCDC88A / GIV / Girdin
Human
IHC WB
Unconjugated
100µg 1ml  $860.00

CCDC88A / GIV / Girdin Antibody (aa1383-1432) LS-C118360
Rabbit Polyclonal (IgG) to Human CCDC88A / GIV / Girdin
Mouse, Human
IHC IHC-P Peptide-ELISA
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Girdin Antibody. The picture on the right is blocked with the synthesized peptide.

CCDC88A / GIV / Girdin Antibody (phospho-Ser1417) LS-C198999
Rabbit Polyclonal (IgG) to Human CCDC88A / GIV / Girdin
Mouse, Human
IHC IHC-P Peptide-ELISA
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using Girdin (Phospho-Ser1417) Antibody. The picture on the right is blocked with the phospho peptide.

CCDC88A / GIV / Girdin Antibody LS-C402974
Rabbit Polyclonal (IgG) to Human CCDC88A / GIV / Girdin
Mouse, Human
ELISA IHC
Unconjugated
20µl 0.2mg/ml  $205.00; 60µl 0.2mg/ml  $235.00; 120µl 0.2mg/ml  $295.00; 200µl 0.2mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human colon cancer using CCDC88A Polyclonal Antibody at dilution of 1:50.
Immunohistochemistry of paraffin-embedded Human colon cancer using CCDC88A Polyclonal Antibody at dilution of 1:50.

CCDC88A / GIV / Girdin Antibody LS-C761184
Rabbit Polyclonal to Human CCDC88A / GIV / Girdin
Mouse, Rat, Human
IHC WB
Unconjugated
30µl 1mg/ml  $205.00; 100µl 1mg/ml  $245.00; 200µl 1mg/ml  $305.00
Immunohistochemical analysis of Girdin staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Western blot analysis of Girdin expression in K562 (A), CT26 (B), rat testis (C) whole cell lysates.

CCDC88A / GIV / Girdin Antibody (aa425-475) LS-C289801
Rabbit Polyclonal (IgG) to Human CCDC88A / GIV / Girdin
Human
IP
Unconjugated
100µl 1mg/ml  $395.00
Showing 1-10 of 10 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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