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Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer (PubMed:24793695, PubMed:24793696). Required for localization of CUL7 to the centrosome (PubMed:24793695).
Gene Name: | Coiled-coil Domain Containing 8 |
Synonyms: | CCDC8, 3M3, PPP1R20, p90 |
Target Sequences: | NM_032040 NP_114429.2 Q9H0W5 |
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