CCAR2 / KIAA1967

cell cycle and apoptosis regulator 2

Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis. Inhibits SUV39H1 methyltransferase activity. As part of a histone H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors. Plays a critical role in maintaining genomic stability and cellular integrity following UV-induced genotoxic stress.

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Products

Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

CCAR2 / KIAA1967 (4)

Publications

No (4)

Tag

GST (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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CCAR2 / KIAA1967 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G110736

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

102.7 kDa

Price:

100 µg/$710

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Human CCAR2 / KIAA1967 Protein (Recombinant GST) (Full Length) - LS-G34807

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

65.45 kDa

Price:

10 µg/$479; 25 µg/$670

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Human CCAR2 / KIAA1967 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72138

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

102.7 kDa

Price:

20 µg/$1,107

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Human CCAR2 / KIAA1967 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91497

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

102.7 kDa

Price:

20 µg/$215

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