CC2D1A

coiled-coil and C2 domain containing 1A

Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses (By similarity). Plays distinct roles depending on its localization. When cytoplasmic, acts as a scaffold protein in the PI3K/PDK1/AKT pathway. Repressor of HTR1A when nuclear. In the centrosome, regulates spindle pole localization of the cohesin subunit SCC1/RAD21, thereby mediating centriole cohesion during mitosis.

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Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

CC2D1A (4)

Publications

No (4)

Tag

GST (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human CC2D1A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84658

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

103.9 kDa

Price:

20 µg/$150

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Human CC2D1A Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69443

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

103.9 kDa

Price:

20 µg/$1,107

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Human CC2D1A Protein (Recombinant GST) (Full Length) - LS-G34084

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

130.5 kDa

Price:

10 µg/$479; 25 µg/$670

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CC2D1A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101494

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

103.9 kDa

Price:

100 µg/$494

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