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CBX8

chromobox homolog 8

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Gene Name: chromobox homolog 8
Synonyms: CBX8, Chromobox protein homolog 8, Pc class 3 homolog, Polycomb 3, RC1, PC3, Polycomb 3 homolog, Rectachrome 1, Chromobox homolog 8, HPC3
Target Sequences: NM_020649 NP_065700.1 Q9HC52

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
CBX8 (3)
No (3)
GST (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
CBX8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
43.2 kDa
20 µg/$150
CBX8 Protein - 12.5% SDS-PAGE of human CBX8 stained with Coomassie Blue
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Wheat Germ Extract
GST
69.8 kDa
2 µg/$439
CBX8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
43.2 kDa
100 µg/$494
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).