CBFA1 / RUNX2

runt-related transcription factor 2

Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. In osteoblasts, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity). Inhibits KAT6B-dependent transcriptional activation.

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Products

Proteins (8)

Type

Over-Expression Lysate (4)

Recombinant (4)

Target

CBFA1 / RUNX2 (8)

Publications

No (8)

Tag

GST, N-terminus (2)

His (2)

Myc-DDK (Flag) (4)

Species

Human (5)

Mouse (1)

Source

293T Cells (2)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (2)

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Mouse CBFA1 / RUNX2 Protein (Recombinant His) (aa125-352) - LS-G13214

Source:

E. coli

Tag:

His

Molecular Weight:

26.5 kDa

Price:

10 µg/$289; 50 µg/$492; 100 µg/$785; 200 µg/$982; 1 mg/$2,119; 500 µg/$1,646; 5 mg/$3,431; 2 mg/$2,309

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Human CBFA1 / RUNX2 Protein (Recombinant GST, N-terminus) (aa251-350) - LS-G57998

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human CBFA1 / RUNX2 Protein (Recombinant GST, N-terminus) (aa311-450) - LS-G58001

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human CBFA1 / RUNX2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81230

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.9 kDa

Price:

20 µg/$215

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Human CBFA1 / RUNX2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81231

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

64.44 kDa

Price:

20 µg/$215

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Human CBFA1 / RUNX2 Protein (Recombinant His) (aa299-521) - LS-G13210

Source:

E. coli

Tag:

His

Molecular Weight:

26.4 kDa

Price:

10 µg/$285; 50 µg/$467; 200 µg/$932; 1 mg/$2,058; 500 µg/$1,590; 5 mg/$3,263; 2 mg/$2,246

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CBFA1 / RUNX2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100271

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.9 kDa

Price:

100 µg/$710

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CBFA1 / RUNX2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99287

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

64.44 kDa

Price:

100 µg/$710

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