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CATSPER1 / CATSPER

cation channel, sperm associated 1

Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. Activated by extracellular progesterone and prostaglandins following the sequence: progesterone > PGF1-alpha = PGE1 > PGA1 > PGE2 >> PGD2. The primary effect of progesterone activation is to shift voltage dependence towards more physiological, negative membrane potentials; it is not mediated by metabotropic receptors and second messengers. Sperm capacitation enhances the effect of progesterone by providing additional negative shift. Also activated by the elevation of intracellular pH.

Gene Name: cation channel, sperm associated 1
Family/Subfamily: Ion Channel , Calcium channel - sperm associated
Synonyms: CATSPER1, CATSPER, HCatSper, Sperm ion channel, SPGF7
Target Sequences: NM_053054 NP_444282.3 Q8NEC5

☰ Filters
Antibodies (12)
Proteins (2)
Primary (12)
Recombinant (2)
CATSPER1 / CATSPER (14)
Human (11)
Mouse (3)
Rat (2)
Monkey (1)
IHC (1)
WB (12)
ELISA (7)
Peptide-ELISA (1)
rabbit (11)
rabbit-new zealand white (1)
IgG (7)
polyclonal pc (12)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (7)
aa36-65 (7)
Internal (1)
No (14)
GST (1)
GST, N-terminus (1)
Human (2)
Wheat Germ Extract (2)
Purified (1)
CATSPER1 / CATSPER Antibody - Western blot analysis of CATSPER1 expression in MCF7 (A); NS-1 (B); PC12 (C) whole cell lysates.
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CATSPER1 / CATSPER Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human, Monkey
WB
Unconjugated
100 µl/$299
Select
CATSPER1 / CATSPER Rabbit-New Zealand White anti-Mouse Polyclonal Antibody
Mouse
IHC, WB
Unconjugated
100 µl/$393
Select
CATSPER1 / CATSPER Rabbit anti-Human Polyclonal (aa36-65) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
CATSPER1 / CATSPER Rabbit anti-Human Polyclonal (aa36-65) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
CATSPER1 / CATSPER Rabbit anti-Human Polyclonal (aa36-65) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
CATSPER1 / CATSPER Rabbit anti-Human Polyclonal (aa36-65) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
CATSPER1 / CATSPER Rabbit anti-Human Polyclonal (aa36-65) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
CATSPER1 / CATSPER Rabbit anti-Human Polyclonal (aa36-65) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
CATSPER1 / CATSPER Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
CATSPER1 / CATSPER Antibody - Western blot analysis of CATSPER1 using K562 whole cells lysates
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CATSPER1 / CATSPER Rabbit anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CATSPER1 / CATSPER Antibody - CATSPER1 Antibody western blot of HepG2 cell line lysates (35 ug/lane). The CATSPER1 antibody detected the CATSPER1 protein (arrow).
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CATSPER1 / CATSPER Rabbit anti-Human Polyclonal (aa36-65) Antibody
Human
WB
Unconjugated
400 µl/$393
CATSPER1 / CATSPER Antibody - Western blot of CATSPER1 antibody at 1:500 dilution. Lane 1: MCF-7 whole cell lysate. Lane 2: sp2/0 whole cell lysate. Lane 3: PC12 whole cell lysate.
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CATSPER1 / CATSPER Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
CATSPER1 / CATSPER Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CATSPER1 / CATSPER Protein - 12.5% SDS-PAGE of human CATSPER1 stained with Coomassie Blue
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Wheat Germ Extract
GST
116.5 kDa
2 µg/$439
Viewing 1-14 of 14 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).