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CAT / Catalase

catalase

CAT / Catalase is catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.

Gene Name: catalase
Synonyms: CAT, Catalase
Target Sequences: NM_001752 NP_001743.1 P04040

Publications (4)

1
A novel giant peroxisomal superoxide dismutase motif-containing protein. Toutzaris D, Lewerenz J, Albrecht P, Jensen LT, Letz J, Geerts A, Golz S, Methner A. Free radical biology & medicine. 2010 48:811-20. [PubMed:20045724]
2
Effect of specific activation of ?-aminobutyric acid receptor in vivo on oxidative stress-induced damage after extended hepatectomy. Gardner LB, Hori T, Chen F, Baine AM, Hata T, Uemoto S, Nguyen JH. Hepatology research : the official journal of the Japan Society of Hepatology. 2012 42:1131-40. (WB; Mouse) [Full Text Article] [PubMed:22583816] [PMC:PMC3438378]
3
Pretreatment of liver grafts in vivo by ?-aminobutyric acid receptor regulation reduces cold ischemia/warm reperfusion injury in rat. Hori T, Gardner LB, Hata T, Chen F, Baine AM, Uemoto S, Nguyen JH. Annals of transplantation : quarterly of the Polish Transplantation Society. 2013 18:299-313. (WB; Rat) [Full Text Article] [PubMed:23792534] [PMC:PMC3912510]
4
Oxidative stress and extracellular matrices after hepatectomy and liver transplantation in rats. Hori T, Uemoto S, Chen F, Gardner LB, Baine AM, Hata T, Kogure T, Nguyen JH. World journal of hepatology. 2014 6:72-84. (WB; Rat) [PubMed:24575166] [PMC:PMC3934637]
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☰ Filters
Products
Proteins (15)
Over-Expression Lysate (2)
Recombinant (13)
CAT / Catalase (15)
No (15)
GST (1)
GST, N-terminus (1)
His (6)
His-S (2)
Myc-DDK (Flag) (3)
Human (12)
Mouse (2)
293T Cells (1)
Baculovirus (1)
E. coli (9)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (4)
Low endotoxin level (3)
Biologically active (1)
CAT / Catalase Protein
Select
E. coli
His
Biologically active
100 µg/$361; 500 µg/$739; 20 µg/$261
CAT / Catalase Protein - Purified recombinant protein CAT was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
59.6 kDa
20 µg/$1,107
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
59.7 kDa
10 µg/$344; 50 µg/$584
CAT / Catalase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
59.6 kDa
100 µg/$494
CAT / Catalase Protein - 12.5% SDS-PAGE of human CAT stained with Coomassie Blue
Select
Wheat Germ Extract
GST
86.2 kDa
10 µg/$479; 25 µg/$670
CAT / Catalase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
59.6 kDa
20 µg/$150
CAT / Catalase Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Select
Baculovirus
His
Less than 1.0 EU/µg protein (determined by LAL method).
61.9 kDa
50 µg/$793
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
59.7kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157
CAT / Catalase Protein - Recombinant Catalase By SDS-PAGE
Select
E. coli
His-S
19.7 kDa
10 µg/$243; 50 µg/$291; 100 µg/$339; 200 µg/$402; 1 mg/$1,156; 500 µg/$802; 5 mg/$1,982; 2 mg/$1,298
CAT / Catalase Protein - Recombinant Catalase By SDS-PAGE
Select
E. coli
His
58.9 kDa
10 µg/$243; 50 µg/$291; 100 µg/$339; 200 µg/$402; 1 mg/$1,156; 500 µg/$802; 5 mg/$2,144
Select
E. coli
His
15.5 kDa
10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723
Select
E. coli
His
17.4 kDa
10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723
Select
E. coli
His
19.9 kDa
10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723
Select
E. coli
His-S
15.5 kDa
10 µg/$243; 50 µg/$291; 100 µg/$339; 200 µg/$402; 1 mg/$1,156; 500 µg/$802; 5 mg/$1,982; 2 mg/$1,298
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).