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CAT / Catalase

catalase

CAT / Catalase is catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.

Gene Name: catalase
Synonyms: CAT, Catalase
Target Sequences: NM_001752 NP_001743.1 P04040

Publications (4)

1
A novel giant peroxisomal superoxide dismutase motif-containing protein. Toutzaris D, Lewerenz J, Albrecht P, Jensen LT, Letz J, Geerts A, Golz S, Methner A. Free radical biology & medicine. 2010 48:811-20. [PubMed:20045724]
2
Effect of specific activation of ?-aminobutyric acid receptor in vivo on oxidative stress-induced damage after extended hepatectomy. Gardner LB, Hori T, Chen F, Baine AM, Hata T, Uemoto S, Nguyen JH. Hepatology research : the official journal of the Japan Society of Hepatology. 2012 42:1131-40. (WB; Mouse) [Full Text Article] [PubMed:22583816] [PMC:PMC3438378]
3
Pretreatment of liver grafts in vivo by ?-aminobutyric acid receptor regulation reduces cold ischemia/warm reperfusion injury in rat. Hori T, Gardner LB, Hata T, Chen F, Baine AM, Uemoto S, Nguyen JH. Annals of transplantation : quarterly of the Polish Transplantation Society. 2013 18:299-313. (WB; Rat) [Full Text Article] [PubMed:23792534] [PMC:PMC3912510]
4
Oxidative stress and extracellular matrices after hepatectomy and liver transplantation in rats. Hori T, Uemoto S, Chen F, Gardner LB, Baine AM, Hata T, Kogure T, Nguyen JH. World journal of hepatology. 2014 6:72-84. (WB; Rat) [PubMed:24575166] [PMC:PMC3934637]
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CAT / Catalase Antibody - Anti-Catalase antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2 ug/ml.
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CAT / Catalase Goat anti-Human Polyclonal (aa498-511) Antibody
Mouse, Dog, Hamster, Horse, Bat, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
CAT / Catalase Antibody - Anti-Catalase antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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CAT / Catalase Rabbit anti-Bovine Polyclonal Antibody
Bovine
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
CAT / Catalase Antibody - Anti-Catalase antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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CAT / Catalase Rabbit anti-Human Polyclonal (aa361-410) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$460
CAT / Catalase Protein
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E. coli
His
Biologically active
100 µg/$361; 500 µg/$739; 20 µg/$261
CAT / Catalase ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
CAT / Catalase Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CAT / Catalase Mouse anti-Human Monoclonal (1B6) Antibody
Dog, Rat, Human, Monkey
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
CAT / Catalase Antibody - CAT / Catalase antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CAT / Catalase Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$424
CAT / Catalase ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$854
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CAT / Catalase Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ICC, IP, WB
FITC Conjugated
100 µl/$362; 200 µl/$427; 500 µl/$666; 1 ml/$826
CAT / Catalase ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$893
CAT / Catalase Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-CAT mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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CAT / Catalase Mouse anti-Human Monoclonal (OTI1B8) Antibody
Human, Monkey
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
CAT / Catalase Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-CAT mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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CAT / Catalase Mouse anti-Human Monoclonal (Carrier-free) (OTI1B8) Antibody
Human, Monkey
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
CAT / Catalase Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CAT / Catalase Mouse anti-Human Monoclonal (Carrier-free) (1B6) Antibody
Dog, Rat, Human, Monkey
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
CAT / Catalase Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-CAT mouse monoclonal antibody.
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CAT / Catalase Mouse anti-Human Monoclonal (OTI3C3) Antibody
Dog, Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
CAT / Catalase Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-CAT mouse monoclonal antibody.
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CAT / Catalase Mouse anti-Human Monoclonal (Carrier-free) (OTI3C3) Antibody
Dog, Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
CAT / Catalase Antibody - 1:100 staining mouse kidney tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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CAT / Catalase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CAT / Catalase Antibody - Western Blot of Rabbit Anti-Catalase antibody. Lane R: Reduced samples of purified Catalase. Lane NR: Non-reduced samples of purified Catalase. Load: ~1ug of protein per lane. Primary antibody: Catalase antibody at 1:1000 for overnight at 4 degrees C. Secondary antibody: Dylight488 alpha rabbit secondary antibody at 1:10,000 for 1.5 hrs at RT. Block: MB-070 overnight at 4 degrees C. Predicted/Observed size: 59.9 kDa, 55 kDa for Catalase. Other band(s): none. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CAT / Catalase Rabbit anti-Bovine Polyclonal (Lyophilized) (HRP) Antibody
Bovine
ELISA, WB
HRP Conjugated, Lyophilized
100 µg/$552
CAT / Catalase Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CAT / Catalase Goat anti-Human Polyclonal Antibody
Mouse, Dog, Rat, Human, Monkey
IHC-P, WB
Unconjugated
100 µl/$460
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CAT / Catalase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
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CAT / Catalase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
CAT / Catalase Antibody - Formalin-fixed and paraffin-embedded human lung carcinoma reacted with CAT Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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CAT / Catalase Rabbit anti-Human Polyclonal (aa152-180) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
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CAT / Catalase Rabbit anti-Bovine Polyclonal Antibody
Bovine
ELISA, IF, IHC, WB
Unconjugated
10 mg/$335
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CAT / Catalase Rabbit anti-Bovine Polyclonal Antibody
Bovine
ELISA, IF, IHC, WB
Unconjugated
1 mg/$520
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CAT / Catalase Rabbit anti-Bovine Polyclonal (Biotin) Antibody
Bovine
ELISA, IF, IHC, WB
Biotin Conjugated
1 ml/$438
CAT / Catalase ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Fish
125 - 2000 mU/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$1,041
Viewing 1-25 of 183 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).