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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CASP9 / Caspase 9

caspase 9, apoptosis-related cysteine peptidase

CASP9 / Caspase 9 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.

Gene Name: caspase 9, apoptosis-related cysteine peptidase
Family/Subfamily: Protease , Cysteine C14
Synonyms: CASP9, APAF3, CASPASE-9c, ICE-LAP6, MCH6, ICE-like apoptotic protease 6, APAF-3, Apoptotic protease Mch-6, CASP-9, Caspase 9, Caspase-9, PPP1R56
Target Sequences: NM_001229 NP_001220.2 P55211

Publications (1)

1
Apocytochrome c blocks caspase-9 activation and Bax-induced apoptosis. Martin AG, Fearnhead HO. The Journal of biological chemistry. 2002 277:50834-41. [PubMed:12393884]

Filtered by: None
Type
Cell-Based (1)
Cell-Based Phosphorylation (4)
Competitive EIA (1)
Custom (6)
Sandwich (18)
Sandwich CLIA (3)
Target
CASP9 / Caspase 9 (33)
Reactivity
Human (13)
Mouse (8)
Rat (8)
Canine (1)
Chicken (1)
Guinea pig (1)
Monkey (1)
Pig (1)
Porcine (1)
Rabbit (1)
Sheep (1)
Sample Type
Adherent Cell Cultures (5)
Cell Culture Supernatants (2)
Cell Lysates (5)
Plasma (18)
Serum (18)
Tissue Homogenates (12)
Publications
No (33)
Showing 1-25 of 33 results

Human Phospho-CASP9 / Caspase 9 (Tyr153) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1325
Cell-Based Phosphorylation
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1plate  $590.00
LSBio image for ELISA Kit

Human Phospho-CASP9 / Caspase 9 (Ser144) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1326
Cell-Based Phosphorylation
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1plate  $590.00
LSBio image for ELISA Kit

Human Phospho-CASP9 / Caspase 9 (Ser196) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1327
Cell-Based Phosphorylation
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1plate  $590.00
LSBio image for ELISA Kit

Mouse/Human/Rat Phospho-CASP9 / Caspase 9 (Thr125) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1077
Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1plate  $590.00
LSBio image for ELISA Kit

Mouse/Human/Rat CASP9 / Caspase 9 ELISA Kit (Cell-Based ELISA) - LS-F1857
Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1plate  $490.00
LSBio image for ELISA Kit

Human CASP9 / Caspase 9 ELISA Kit (Sandwich ELISA) - LS-F26734
Sandwich
96-Well Strip Plate
Human
5 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $870.00
LSBio image for ELISA Kit

Human CASP9 / Caspase 9 ELISA Kit (Custom ELISA) - LS-F14927
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1plate  $650.00
LSBio image for ELISA Kit

Human CASP9 / Caspase 9 ELISA Kit (CLIA) - LS-F29520
Sandwich CLIA
12 x 8-Well Microstrips
Human
0.313 - 20 ng/ml
Chemiluminescent
Plasma, Serum
1plate  $700.00
LSBio image for ELISA Kit

Pig CASP9 / Caspase 9 ELISA Kit (Sandwich ELISA) - LS-F32146
Sandwich
96-Well Strip Plate
Pig
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1plate  $555.00
LSBio image for ELISA Kit

Rat CASP9 / Caspase 9 ELISA Kit (Sandwich ELISA) - LS-F32361
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1plate  $550.00
LSBio image for ELISA Kit

Mouse CASP9 / Caspase 9 ELISA Kit (Sandwich ELISA) - LS-F32788
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1plate  $790.00
LSBio image for ELISA Kit

Human CASP9 / Caspase 9 ELISA Kit (Sandwich ELISA) - LS-F32787
Sandwich
96-Well Strip Plate
Human
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1plate  $790.00
LSBio image for ELISA Kit

Mouse CASP9 / Caspase 9 ELISA Kit (CLIA) - LS-F30562
Sandwich CLIA
12 x 8-Well Microstrips
Mouse
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1plate  $700.00
LSBio image for ELISA Kit

Rat CASP9 / Caspase 9 ELISA Kit (Sandwich ELISA) - LS-F27373
Sandwich
96-Well Strip Plate
Rat
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $870.00
LSBio image for ELISA Kit

Rat CASP9 / Caspase 9 ELISA Kit (CLIA) - LS-F31155
Sandwich CLIA
12 x 8-Well Microstrips
Rat
0.313 - 20 ng/ml
Chemiluminescent
Plasma, Serum
1plate  $700.00
LSBio image for ELISA Kit

Porcine CASP9 / Caspase 9 ELISA Kit (Sandwich ELISA) - LS-F40394
Sandwich
96-Well Strip Plate
Porcine
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $660.00
LSBio image for ELISA Kit

Chicken CASP9 / Caspase 9 ELISA Kit (Custom ELISA) - LS-F42035
Custom
96-Well Strip Plate
Chicken
15.625 - 1000 ng/ml
Colorimetric - 450nm (TMB)
1plate  $660.00
LSBio image for ELISA Kit

Guinea pig CASP9 / Caspase 9 ELISA Kit (Custom ELISA) - LS-F42037
Custom
96-Well Strip Plate
Guinea pig
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
1plate  $660.00
LSBio image for ELISA Kit

Monkey CASP9 / Caspase 9 ELISA Kit (Custom ELISA) - LS-F42036
Custom
96-Well Strip Plate
Monkey
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1plate  $660.00
LSBio image for ELISA Kit

Rabbit CASP9 / Caspase 9 ELISA Kit (Custom ELISA) - LS-F42038
Custom
96-Well Strip Plate
Rabbit
15.625 - 1000 ng/ml
Colorimetric - 450nm (TMB)
1plate  $660.00
LSBio image for ELISA Kit

Sheep CASP9 / Caspase 9 ELISA Kit (Custom ELISA) - LS-F42040
Custom
96-Well Strip Plate
Sheep
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
1plate  $730.00
LSBio image for ELISA Kit

Mouse CASP9 / Caspase 9 ELISA Kit (Sandwich ELISA) - LS-F52950
Sandwich
96-Well Strip Plate
Mouse
12.5 - 800 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1plate  $770.00
LSBio image for ELISA Kit

Mouse CASP9 / Caspase 9 ELISA Kit (Competitive EIA) - LS-F28242
Competitive EIA
96-Well Strip Plate
Mouse
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $870.00
LSBio image for ELISA Kit

Rat CASP9 / Caspase 9 ELISA Kit (Sandwich ELISA) - LS-F53699
Sandwich
96-Well Strip Plate
Rat
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1plate  $770.00
LSBio image for ELISA Kit

Mouse CASP9 / Caspase 9 ELISA Kit (Sandwich ELISA) - LS-F21324
Sandwich
96-Well Microplate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $590.00
LSBio image for ELISA Kit
Showing 1-25 of 33 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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