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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CASP5 / Caspase 5

caspase 5, apoptosis-related cysteine peptidase

CASP5 / Caspase 5 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.

Gene Name: caspase 5, apoptosis-related cysteine peptidase
Family/Subfamily: Protease , Cysteine C14
Synonyms: CASP5, CASP-5, Caspase 5, Caspase-5, ICE(rel)III, ICEREL-III, ICE(rel)-III, Ich-3, Protease TY, ICH3, Protease ICH-3, TY protease
Target Sequences: NM_004347 NP_004338.3 P51878

Filtered By: None
Target
CASP5 / Caspase 5 (54)
Reactivity
Human (54)
Mouse (12)
Rat (12)
Bovine (8)
Hamster (8)
Monkey (8)
Rabbit (7)
Application
IHC (10)
IHC-P (2)
WB (50)
ELISA (8)
ICC (3)
IF (1)
Peptide-ELISA (2)
Host
rabbit (53)
mouse (1)
Isotype
IgG (44)
IgG1,k (1)
Clonality
monoclonal mc (1)
polyclonal pc (53)
Clone
4F7 (1)
Format
AP Conjugated (4)
APC (1)
APC Conjugated (4)
Biotin Conjugated (8)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (8)
HRP Conjugated (7)
PE Conjugated (5)
Unconjugated (16)
Epitope
aa145-327 (10)
aa251-300 (4)
290-370 aa, C-terminal (1)
80-160 aa, Internal (1)
Asp121 (1)
C-Terminus (1)
Internal (1)
aa102-151 (1)
aa162 (1)
aa312-361 (1)
aa341-386 (1)
Publications
No (54)
Showing 1-25 of 54 results

CASP5 / Caspase 5 Antibody IHC-plus™ LS-B476
Rabbit Polyclonal (IgG) to Human CASP5 / Caspase 5
Human
ELISA ICC IF IHC IHC-P WB
Unconjugated
50µg 1mg/ml  $425.00
Anti-CASP5 / Caspase 5 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Immunofluorescence of Caspase-5 in P815 cells with Caspase-5 antibody at 2 ug/ml.

CASP5 / Caspase 5 Antibody (aa102-151) IHC-plus™ LS-B13450
Rabbit Polyclonal (IgG) to Human CASP5 / Caspase 5
Human
IHC IHC-P Peptide-ELISA WB
Unconjugated
100µl 1mg/ml  $505.00
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)

CASP5 / Caspase 5 Antibody (aa145-327) LS-C314614
Rabbit Polyclonal (IgG) to Human CASP5 / Caspase 5
Human
IHC WB
Unconjugated
20µl 0.5mg/ml  $195.00; 100µl 0.5mg/ml  $245.00; 200µl 0.5mg/ml  $285.00; 1ml 0.5mg/ml  $475.00; 10ml 0.5mg/ml  $1,890.00
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image

CASP5 / Caspase 5 Antibody (aa145-327, HRP) LS-C708226
Rabbit Polyclonal (IgG) to Human CASP5 / Caspase 5
Human
IHC WB
HRP Conjugated
20µl  $205.00; 100µl  $275.00; 200µl  $325.00; 1ml  $620.00; 10ml  $2,460.00
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image

CASP5 / Caspase 5 Antibody (aa145-327, Biotin) LS-C685005
Rabbit Polyclonal (IgG) to Human CASP5 / Caspase 5
Human
IHC WB
Biotin Conjugated
20µl  $205.00; 100µl  $255.00; 200µl  $295.00; 1ml  $515.00; 10ml  $2,085.00
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image

CASP5 / Caspase 5 Antibody (aa145-327, Biotin) LS-C419543
Rabbit Polyclonal (IgG) to Human CASP5 / Caspase 5
Human
ICC WB
Biotin Conjugated
100µl 0.5mg/ml  $355.00

CASP5 / Caspase 5 Antibody (aa145-327, FITC) LS-C691363
Rabbit Polyclonal (IgG) to Human CASP5 / Caspase 5
Human
IHC WB
FITC Conjugated
20µl  $205.00; 100µl  $265.00; 200µl  $315.00; 1ml  $560.00; 10ml  $2,265.00
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image

CASP5 / Caspase 5 Antibody (aa145-327, FITC) LS-C419545
Rabbit Polyclonal (IgG) to Human CASP5 / Caspase 5
Human
ICC WB
FITC Conjugated
100µl 0.5mg/ml  $365.00

CASP5 / Caspase 5 Antibody (aa145-327, Cy3) LS-C699203
Rabbit Polyclonal (IgG) to Human CASP5 / Caspase 5
Human
IHC WB
Cy3 Conjugated
20µl  $235.00; 100µl  $335.00; 200µl  $415.00; 1ml  $950.00; 10ml  $3,780.00
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image

CASP5 / Caspase 5 Antibody (aa145-327, APC) LS-C716090
Rabbit Polyclonal (IgG) to Human CASP5 / Caspase 5
Human
IHC WB
APC Conjugated
20µl  $215.00; 100µl  $295.00; 200µl  $345.00; 1ml  $710.00; 10ml  $4,215.00
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image

CASP5 / Caspase 5 Antibody (aa145-327, PE) LS-C722286
Rabbit Polyclonal (IgG) to Human CASP5 / Caspase 5
Human
IHC WB
PE Conjugated
20µl  $205.00; 100µl  $265.00; 200µl  $315.00; 1ml  $560.00; 10ml  $2,265.00
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image

CASP5 / Caspase 5 Antibody (aa145-327, APC, Cy7) LS-C731285
Rabbit Polyclonal (IgG) to Human CASP5 / Caspase 5
Human
IHC WB
APC, Cy7 Conjugated
20µl  $275.00; 100µl  $425.00; 200µl  $560.00; 1ml  $1,410.00; 10ml  $5,685.00
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image

CASP5 / Caspase 5 Antibody (80-160 aa, Internal) LS-C380469
Rabbit Polyclonal (IgG) to Human CASP5 / Caspase 5
Human
ELISA WB
Unconjugated
100µl 1mg/ml  $265.00
Western blot of Cleaved-Caspase-5 p20 (D121) antibody

CASP5 / Caspase 5 Antibody (290-370 aa, C-terminal) LS-C380468
Rabbit Polyclonal (IgG) to Human CASP5 / Caspase 5
Human
ELISA WB
Unconjugated
100µl 1mg/ml  $265.00
Western blot of Cleaved-Caspase-5 p10 (S331) antibody

CASP5 / Caspase 5 Antibody LS-C464
Rabbit Polyclonal (IgG) to Human CASP5 / Caspase 5
Human
ELISA WB
Unconjugated
100µg 1mg/ml  $365.00
Western blot of caspase-5 in Ramos cells with caspase-5 antibody at (A) 0.5, (B) 1, and (C) 2 ug/ml.

CASP5 / Caspase 5 Antibody (aa312-361) LS-C121053
Rabbit Polyclonal (IgG) to Human CASP5 / Caspase 5
Human
Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Western blot of extracts from 293 cells, treated with etoposide 25 uM 1h, using Caspase 5 (p10, Cleaved-Ser331) Antibody. The lane on the right is treated with the synthesized peptide.

CASP5 / Caspase 5 Antibody (clone 4F7) LS-C179792
Mouse Monoclonal [clone 4F7] (IgG1,k) to Human CASP5 / Caspase 5
Human
WB
Unconjugated
100µg 1mg/ml  $345.00
Western blot Image

CASP5 / Caspase 5 Antibody LS-C677397
Rabbit Polyclonal (IgG) to Human CASP5 / Caspase 5
Human
ELISA
Unconjugated
50µg  $285.00; 100µg  $385.00

CASP5 / Caspase 5 Antibody (aa341-386) LS-C313697
Rabbit Polyclonal to Human CASP5 / Caspase 5
Mouse, Rat, Human
WB
Unconjugated
100µl  $345.00

CASP5 / Caspase 5 Antibody (aa162) LS-C190182
Rabbit Polyclonal (IgG) to Human CASP5 / Caspase 5
Rabbit, Mouse, Bovine, Rat, Hamster, Human, Monkey
WB
Unconjugated
100µg 0.1mg/ml  $495.00

CASP5 / Caspase 5 Antibody (Asp121) LS-C341178
Rabbit Polyclonal to Human CASP5 / Caspase 5
Mouse, Rat, Human
WB
Unconjugated
100µl 1mg/ml  $385.00

CASP5 / Caspase 5 Antibody LS-C48140
Rabbit Polyclonal to Human CASP5 / Caspase 5
Mouse, Bovine, Rat, Hamster, Human, Monkey
WB
Unconjugated
30µg  $245.00; 100µg 500µl  $405.00

CASP5 / Caspase 5 Antibody (C-Terminus) LS-C351913
Rabbit Polyclonal to Human CASP5 / Caspase 5
Mouse, Rat, Human
WB
Unconjugated
100µl 1mg/ml  $245.00
Western blot analysis of Caspase 5 p10 expression in Jurkat (A); mouse liver (B); rat liver (C) whole cell lysates.

CASP5 / Caspase 5 Antibody (Internal) LS-C351914
Rabbit Polyclonal to Human CASP5 / Caspase 5
Mouse, Rat, Human
WB
Unconjugated
100µl 1mg/ml  $245.00
Western blot analysis of Caspase 5 p20 expression in MCF7 (A); mouse kidney (B); rat liver (C) whole cell lysates.

CASP5 / Caspase 5 Antibody (aa251-300) LS-C135479
Rabbit Polyclonal to Human CASP5 / Caspase 5
Human
WB
Unconjugated
100µl 0.5mg/ml  $365.00
CASP5 / Caspase 5 antibody Western blot of A549 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Showing 1-25 of 54 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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