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CASP2 / Caspase 2

caspase 2, apoptosis-related cysteine peptidase

Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1b and IL-18. Although phylogenetically similar to this subfamily, Caspase-2 is thought to be involved in stress-induced apoptosis. Caspase-2 has two major isoforms; overexpression on the long form results in apoptosis while that of the short form suppresses cell death.

Gene Name: caspase 2, apoptosis-related cysteine peptidase
Family/Subfamily: Protease , Cysteine C14
Synonyms: CASP2, CASP-2, Caspase-2, PPP1R57, Protease ICH-1, NEDD-2, Caspase 2, ICH1, NEDD2
Target Sequences: NM_032982 NP_116764.2 P42575

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Antibodies (90)
Proteins (8)
ELISA Kits (7)
Cell-Based (1)
Custom (2)
Primary (90)
Recombinant (8)
Sandwich (4)
CASP2 / Caspase 2 (105)
Human (83)
Mouse (45)
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IHC (23)
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WB (80)
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IP (12)
Peptide-ELISA (6)
rabbit (80)
mouse (6)
rat (4)
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IHCPlus (2)
IgG (42)
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monoclonal mc (10)
polyclonal pc (80)
10C6 (1)
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18E809.3 (1)
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415 (1)
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aa170-325 (8)
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CASP2 / Caspase 2 Antibody - Anti-CASP2 / Caspase 2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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CASP2 / Caspase 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, ICC, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
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CASP2 / Caspase 2 Rat anti-Human Monoclonal Antibody
Mouse, Dog, Rat, Human, Monkey
IP, WB
Unconjugated
100 µg/$735
CASP2 / Caspase 2 Antibody - Anti-CASP2 / Caspase 2 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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CASP2 / Caspase 2 Rabbit anti-Human Polyclonal (aa123-172) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
CASP2 / Caspase 2 Antibody - Western blot analysis of Caspase 2 p18 expression in mouse brain (A); rat brain (B); PC12 UV-treated (C) whole cell lysates.
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CASP2 / Caspase 2 Rabbit anti-Human Polyclonal (Internal) Antibody
Chicken, Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
CASP2 / Caspase 2 Antibody - HeLa cells were fixed, permeabilized, stained using anti-caspase-2, mAb (10C6) and FITC-conjugated goat anti-rat IgG antibodies (green) or rabbit anti-beta-COP and biotinylated goat anti-rabbit; streptavidin Texas Red (red) and DAPI (blue) and examined by confocal microscopy.
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CASP2 / Caspase 2 Rat anti-Human Monoclonal (10C6) Antibody
Mouse, Dog, Rat, Human, Monkey
ELISA, Flo, ICC, IHC, IHC-Fr
Unconjugated
100 µg/$449
CASP2 / Caspase 2 Antibody - Formalin-fixed and paraffin-embedded human lung with CASP2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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CASP2 / Caspase 2 Rabbit anti-Human Polyclonal (aa198-226) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
CASP2 / Caspase 2 Antibody - Staining HepG2 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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CASP2 / Caspase 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CASP2 / Caspase 2 Antibody - Immunofluorescence of monoclonal antibody to CASP2 on HeLa cell . [antibody concentration 10 ug/ml]
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CASP2 / Caspase 2 Mouse anti-Human Monoclonal (1C11) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$423
CASP2 / Caspase 2 Antibody - IHC analysis of Caspase-2 using anti-Caspase-2 antibody. Caspase-2 was detected in paraffin-embedded section of human colon cancer tissue. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1µg/ml rabbit anti-Caspase-2 Antibody overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
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CASP2 / Caspase 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
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CASP2 / Caspase 2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
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CASP2 / Caspase 2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
CASP2 / Caspase 2 Antibody - Western blot of recombinant CASP2 / Caspase 2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CASP2 / Caspase 2 Rabbit anti-Human Polyclonal (aa334-452) Antibody
Human
ICC, IP, WB
Unconjugated
100 µl/$299; 200 µl/$336; 500 µl/$462; 1 ml/$525; 2 ml/$677; 5 ml/$1,136
CASP2 / Caspase 2 Antibody - Western blot analysis of extracts from K562 cells, using Caspase 2 (Ab-157) antibody.
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CASP2 / Caspase 2 Rabbit anti-Human Polyclonal (p157) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
CASP2 / Caspase 2 Antibody - Western blot of Caspase-2 antibody
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CASP2 / Caspase 2 Rabbit anti-Human Polyclonal (100-180 aa) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CASP2 / Caspase 2 Antibody - Immunohistochemistry of paraffin-embedded Human urinary bladder using CASP2 Polyclonal Antibody at dilution of 1:100.
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CASP2 / Caspase 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
CASP2 / Caspase 2 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CASP2 / Caspase 2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$380
CASP2 / Caspase 2 Antibody - IHC of Caspase 2 (K136) pAb in paraffin-embedded human lung carcinoma tissue.
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CASP2 / Caspase 2 Rabbit anti-Human Polyclonal (Lys136) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
CASP2 / Caspase 2 Antibody - Immunohistochemical analysis of Caspase 2 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX. w
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CASP2 / Caspase 2 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$299
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CASP2 / Caspase 2 Rabbit anti-Human Polyclonal (aa198-226) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
200 µl/$952
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CASP2 / Caspase 2 Rabbit anti-Human Polyclonal (aa198-226) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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CASP2 / Caspase 2 Rabbit anti-Human Polyclonal (aa198-226) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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CASP2 / Caspase 2 Rabbit anti-Human Polyclonal (aa198-226) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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CASP2 / Caspase 2 Rabbit anti-Human Polyclonal (aa198-226) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
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CASP2 / Caspase 2 Rabbit anti-Human Polyclonal (100-180 aa) Antibody
Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CASP2 / Caspase 2 Antibody - Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using Caspase 2 (Phospho-Ser157) Antibody. The picture on the right is blocked with the phospho peptide.
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CASP2 / Caspase 2 Rabbit anti-Human Polyclonal (pSer157) Antibody
Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
Viewing 1-25 of 105 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).