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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CASP2 / Caspase 2

caspase 2, apoptosis-related cysteine peptidase

Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1b and IL-18. Although phylogenetically similar to this subfamily, Caspase-2 is thought to be involved in stress-induced apoptosis. Caspase-2 has two major isoforms; overexpression on the long form results in apoptosis while that of the short form suppresses cell death.

Gene Name: caspase 2, apoptosis-related cysteine peptidase
Family/Subfamily: Protease , Cysteine C14
Synonyms: CASP2, CASP-2, Caspase-2, PPP1R57, Protease ICH-1, NEDD-2, Caspase 2, ICH1, NEDD2
Target Sequences: NM_032982 NP_116764.2 P42575

Filtered by: None
Target
CASP2 / Caspase 2 (94)
Reactivity
Human (82)
Mouse (50)
Rat (25)
Bat (2)
Bovine (2)
Chicken (3)
Chimpanzee (1)
Dog (6)
Gibbon (1)
Guinea pig (2)
Hamster (2)
Horse (2)
Monkey (6)
Orangutan (1)
Pig (2)
Rabbit (1)
Sheep (1)
Application
IHC (53)
IHC-Fr (2)
IHC-P (12)
WB (84)
Flo (4)
ELISA (26)
ICC (13)
IF (2)
IP (13)
Peptide-ELISA (4)
Host
rabbit (84)
mouse (5)
rat (5)
Isotype
IgG (37)
IgG1 (2)
IgG2a (2)
IgG2a,k (3)
IgG2b (1)
IgG2b,k (1)
IgM (2)
Clonality
monoclonal mc (11)
polyclonal pc (83)
Clone
10C6 (1)
11B4 (1)
18E809.3 (1)
1C10 (1)
1C11 (1)
415 (1)
SB123a (1)
Format
AP Conjugated (2)
APC (3)
APC Conjugated (5)
Biotin Conjugated (8)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (8)
HRP Conjugated (7)
Magnetic beads Conjugated (1)
PE Conjugated (5)
Sepharose Conjugated (1)
Unconjugated (51)
Epitope
aa170-333 (10)
aa170-325 (8)
aa334-452 (8)
aa198-226 (7)
C-Terminus (6)
aa2-452 (4)
aa301-350 (4)
Internal (3)
100-180 aa (2)
N-Terminus (2)
120-200 aa, Internal (1)
250-330 aa, Internal (1)
Gly170 (1)
Lys136 (1)
Thr325 (1)
aa123-172 (1)
aa151-200 (1)
aa276-325 (1)
aa32-169 (1)
aa378-409 (1)
aa417-439 (1)
pSer157 (1)
Publications
No (94)
Showing 1-25 of 94 results

CASP2 / Caspase 2 Antibody IHC-plus™ LS-B475
Rabbit Polyclonal (IgG) to Human CASP2 / Caspase 2
Mouse, Human
ELISA ICC IHC IHC-P WB
Unconjugated
0.05mg 1mg/ml  $425.00
Anti-CASP2 / Caspase 2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

CASP2 / Caspase 2 Antibody LS-C497480
Rabbit Monoclonal to Human CASP2 / Caspase 2
Mouse, Rat, Human
Flo IF IHC WB
Unconjugated
50µl  $295.00; 100µl  $385.00; 200µl  $560.00
Immunohistochemistry of paraffin-embedded mouse kidney using CASP2 antibodyat dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human lung using CASP2 antibodyat dilution of 1:100 (40x lens).

CASP2 / Caspase 2 Antibody IHC-plus™ LS-B8728
Rabbit Polyclonal (IgG) to Mouse CASP2 / Caspase 2
Mouse, Rat, Human
IHC IHC-P WB
Unconjugated
50µg 250µl 0.2mg/ml  $425.00
Anti-CASP2 / Caspase 2 antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Western blot of Caspase 2 antibody.

CASP2 / Caspase 2 Antibody LS-C12464
Rat Monoclonal (IgG2a) to Human CASP2 / Caspase 2
Mouse, Dog, Rat, Human, Monkey
IP WB
Unconjugated
100µg  $695.00

CASP2 / Caspase 2 Antibody (aa123-172) IHC-plus™ LS-B7657
Rabbit Polyclonal (IgG) to Human CASP2 / Caspase 2
Human
IHC IHC-P Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-CASP2 / Caspase 2 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Western blot analysis of lysates from K562, using Caspase 2 Antibody. The lane on the right is blocked with the synthesized peptide.

CASP2 / Caspase 2 Antibody (Internal) LS-C351907
Rabbit Polyclonal to Human CASP2 / Caspase 2
Chicken, Mouse, Rat, Human
WB
Unconjugated
100µl 1mg/ml  $245.00
Western blot analysis of Caspase 2 p18 expression in mouse brain (A); rat brain (B); PC12 UV-treated (C) whole cell lysates.

CASP2 / Caspase 2 Antibody LS-C12462
Rat Monoclonal (IgG2a) to Human CASP2 / Caspase 2
Mouse, Dog, Rat, Human, Monkey
ELISA Flo ICC IHC IHC-Fr
Unconjugated
100µg  $695.00

CASP2 / Caspase 2 Antibody (aa334-452) LS-C293202
Rabbit Polyclonal to Human CASP2 / Caspase 2
Human
ICC IHC IP WB
Unconjugated
20µl 0.5mg/ml  $195.00; 100µl 0.5mg/ml  $245.00; 200µl 0.5mg/ml  $285.00; 1ml 0.5mg/ml  $475.00; 10ml 0.5mg/ml  $1,875.00
Immunohistochemistry - Paraffin Image
Western blot of recombinant CASP2 / Caspase 2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

CASP2 / Caspase 2 Antibody (aa334-452, HRP) LS-C706941
Rabbit Polyclonal to Human CASP2 / Caspase 2
Human
ICC IHC IP WB
HRP Conjugated
20µl  $205.00; 100µl  $275.00; 200µl  $325.00; 1ml  $605.00; 10ml  $2,445.00
Immunohistochemistry - Paraffin Image
Western blot of recombinant CASP2 / Caspase 2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

CASP2 / Caspase 2 Antibody (aa334-452, Biotin) LS-C298240
Rabbit Polyclonal to Human CASP2 / Caspase 2
Human
ICC IHC IP WB
Biotin Conjugated
100µl 0.5mg/ml  $355.00
Immunohistochemistry - Paraffin Image
Western blot of recombinant CASP2 / Caspase 2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

CASP2 / Caspase 2 Antibody (aa334-452, FITC) LS-C302397
Rabbit Polyclonal to Human CASP2 / Caspase 2
Human
ICC IHC IP WB
FITC Conjugated
100µl 0.5mg/ml  $365.00
Immunohistochemistry - Paraffin Image
Western blot of recombinant CASP2 / Caspase 2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

CASP2 / Caspase 2 Antibody (aa334-452, Cy3) LS-C697918
Rabbit Polyclonal to Human CASP2 / Caspase 2
Human
ICC IHC IP WB
Cy3 Conjugated
20µl  $235.00; 100µl  $335.00; 200µl  $415.00; 1ml  $935.00; 10ml  $3,765.00
Immunohistochemistry - Paraffin Image
Western blot of recombinant CASP2 / Caspase 2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

CASP2 / Caspase 2 Antibody (aa334-452, APC, Cy7) LS-C730007
Rabbit Polyclonal to Human CASP2 / Caspase 2
Human
ICC IHC IP WB
APC, Cy7 Conjugated
20µl  $275.00; 100µl  $425.00; 200µl  $560.00; 1ml  $1,410.00; 10ml  $5,640.00
Immunohistochemistry - Paraffin Image
Western blot of recombinant CASP2 / Caspase 2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

CASP2 / Caspase 2 Antibody (aa334-452, APC) LS-C738461
Rabbit Polyclonal to Human CASP2 / Caspase 2
Human
ICC IHC IP WB
APC Conjugated
20µl  $215.00; 100µl  $295.00; 200µl  $345.00; 1ml  $710.00
Immunohistochemistry - Paraffin Image
Western blot of recombinant CASP2 / Caspase 2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

CASP2 / Caspase 2 Antibody (aa334-452, PE) LS-C721000
Rabbit Polyclonal to Human CASP2 / Caspase 2
Human
ICC IHC IP WB
PE Conjugated
20µl  $205.00; 100µl  $265.00; 200µl  $315.00; 1ml  $560.00; 10ml  $2,250.00
Immunohistochemistry - Paraffin Image
Western blot of recombinant CASP2 / Caspase 2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

CASP2 / Caspase 2 Antibody (clone 10C6) LS-C344796
Rat Monoclonal [clone 10C6] (IgG2a,k) to Human CASP2 / Caspase 2
Mouse, Dog, Rat, Human, Monkey
ELISA Flo ICC IHC IHC-Fr
Unconjugated
100µg  $395.00
HeLa cells were fixed, permeabilized, stained using anti-caspase-2, mAb (10C6) and FITC-conjugated goat anti-rat IgG antibodies (green) or rabbit anti-beta-COP and biotinylated goat anti-rabbit; streptavidin Texas Red (red) and DAPI (blue) and examined by confocal microscopy.
Flow cytometry data of 293T cells transiently transfected with HA-tagged caspase-2, fixed with 1% PFA, permeabilized with saponin and stained intracellularly with using anti-caspase-2, mAb (10C6) or positive control anti-HA.

CASP2 / Caspase 2 Antibody (aa198-226) LS-C98873
Rabbit Polyclonal to Human CASP2 / Caspase 2
Human
Flo IHC IHC-P WB
Unconjugated
400µl  $325.00
Formalin-fixed and paraffin-embedded human lung with CASP2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Western blot of CASP2 antibody in HL60, K562, Ramos and NIH-3T3 cell line lysates(35 ug/lane). CASP2 (arrow) was detected using the purified antibody.

CASP2 / Caspase 2 Antibody IHC-plus™ LS-B5926
Rabbit Polyclonal (IgG2b,k) to Human CASP2 / Caspase 2
Human
IHC IHC-P WB
Unconjugated
50µl  $425.00
Anti-CASP2 / Caspase 2 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Anti-CASP2 / Caspase 2 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.

CASP2 / Caspase 2 Antibody (C-Terminus) LS-C51685
Rabbit Polyclonal to Human CASP2 / Caspase 2
Mouse, Rat, Human
IHC IHC-P IP WB
Unconjugated
200µg 1000µl 0.2mg/ml  $295.00

CASP2 / Caspase 2 Antibody (clone 1C11) LS-C196816
Mouse Monoclonal [clone 1C11] (IgG2a,k) to Human CASP2 / Caspase 2
Human
ELISA IF WB
Unconjugated
100µg  $355.00
Immunofluorescence of monoclonal antibody to CASP2 on HeLa cell . [antibody concentration 10 ug/ml]

CASP2 / Caspase 2 Antibody LS-C661676
Rabbit Polyclonal (IgG) to Human CASP2 / Caspase 2
Human
ELISA IHC WB
Unconjugated
100µg  $435.00

CASP2 / Caspase 2 Antibody LS-C661678
Rabbit Polyclonal (IgG) to Human CASP2 / Caspase 2
Human
ELISA IHC WB
Unconjugated
100µg  $405.00

CASP2 / Caspase 2 Antibody (aa170-325) LS-C293201
Rabbit Polyclonal to Human CASP2 / Caspase 2
Mouse, Human
IHC WB
Unconjugated
20µl 0.5mg/ml  $195.00; 100µl 0.5mg/ml  $245.00; 200µl 0.5mg/ml  $285.00; 1ml 0.5mg/ml  $475.00; 10ml 0.5mg/ml  $1,890.00
Immunohistochemistry - Paraffin Image
Western blot of recombinant CASP2 / Caspase 2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

CASP2 / Caspase 2 Antibody (100-180 aa) LS-C382449
Rabbit Polyclonal (IgG) to Human CASP2 / Caspase 2
Human
ELISA IHC WB
Unconjugated
100µl 1mg/ml  $265.00
Western blot of Caspase-2 antibody
Western blot of Caspase-2 antibody

CASP2 / Caspase 2 Antibody LS-C403732
Rabbit Polyclonal (IgG) to Human CASP2 / Caspase 2
Mouse, Rat, Human
ELISA IHC WB
Unconjugated
20µl 0.6mg/ml  $205.00; 60µl 0.6mg/ml  $235.00; 120µl 0.6mg/ml  $295.00; 200µl 0.6mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human urinary bladder using CASP2 Polyclonal Antibody at dilution of 1:100.
Western blot analysis of Human fetal kidney and lung tissue, using CASP2 Polyclonal Antibody at dilution of 1:950.
Showing 1-25 of 94 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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