Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
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Caspases are produced as zymogens composed of a prodomain plus a large subunit and a small subunit, and require proteolytic processing at internal aspartate residues to generate an active dimeric enzyme. Caspase-13 induces cell death when overexpressed in mammalian cells and is activated by caspase-8, the initiating caspase in the apoptotic cascade. FROM NCBI: DISCONTINUED: LocusID 8628 was defined by AF078533 which has been reported to be (PubMed ID: 11478774) of bovine origin. There is no evidence for this sequence in human.
|Gene Name:||CASP13 / Caspase 13|
|Family/Subfamily:||Protease , Cysteine C14|
|Target Sequences:||AF078533 AAC28380.1|
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