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CASP10 / Caspase 10

caspase 10, apoptosis-related cysteine peptidase

CASP10 / Caspase 10 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene Name: caspase 10, apoptosis-related cysteine peptidase
Family/Subfamily: Protease , Cysteine C14
Synonyms: CASP10, ALPS2, Caspase-10, Caspase 10, CASP-10, FADD-like ICE2, FLICE2, MCH4, ICE-like apoptotic protease 4, Apoptotic protease Mch-4
Target Sequences: NM_001230 NP_001221.2 Q92851

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Products
Proteins (7)
Recombinant (7)
CASP10 / Caspase 10 (7)
No (7)
6His, C-terminus (2)
GST (1)
GST, N-terminus (2)
His, N-Terminal (1)
His-T7 (1)
Human (7)
E. coli (4)
Wheat Germ Extract (3)
Purified (2)
Low endotoxin level (2)
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E. coli
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
30.1 kDa
10 µg/$344; 50 µg/$584
CASP10 / Caspase 10 Protein
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E. coli
His, N-Terminal
58.8 kDa
50 µg/$419
CASP10 / Caspase 10 Protein - Recombinant  Caspase 10 By SDS-PAGE
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E. coli
His-T7
30.6 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
CASP10 / Caspase 10 Protein - 12.5% SDS-PAGE of human CASP10 stained with Coomassie Blue
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Wheat Germ Extract
GST
81 kDa
2 µg/$439
CASP10 / Caspase 10 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CASP10 / Caspase 10 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Select
E. coli
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
30.1kD
10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353
Viewing 1-7 of 7 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).