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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
Contact Us
LSBio
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Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
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CASP1 / Caspase 1

caspase 1, apoptosis-related cysteine peptidase

CASP1 / Caspase 1 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.

Gene Name: caspase 1, apoptosis-related cysteine peptidase
Family/Subfamily: Protease , Cysteine C14
Synonyms: CASP1, Caspase-1, CASP-1, CASP1 nirs variant 1, Caspase 1, ICE, ICE-like protease, IL-1 beta-converting enzyme, IL-1BC, IL1BC, IL1BCE, p45, IL1B-convertase, Interleukin-1 beta convertase
Target Sequences: NM_001223 NP_001214.1 P29466

Viewing 1-25 of 124 items
CASP1 / Caspase 1 Antibody - Anti-Caspase 1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.
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Mouse Monoclonal [clone 14F468] (IgG1,k) to Human CASP1 / Caspase 1
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50µg   1mg/ml   $425.00
CASP1 / Caspase 1 Antibody - Anti-Caspase 1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
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Rabbit Polyclonal to Human CASP1 / Caspase 1
Human
IHC, IHC-P
Unconjugated
250µl   $425.00
CASP1 / Caspase 1 Antibody - Anti-Caspase 1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Rabbit Polyclonal (IgG) to Human CASP1 / Caspase 1
Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.05mg   1mg/ml   $425.00
CASP1 / Caspase 1 Antibody - Anti-Caspase 1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Rabbit Polyclonal (IgG) to Human CASP1 / Caspase 1
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05mg   1mg/ml   $425.00
CASP1 / Caspase 1 Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using CASP1 Antibody at dilution of 1:100
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Rabbit Polyclonal (IgG) to Human CASP1 / Caspase 1
Human
ELISA, IHC, WB
Unconjugated
50µg   $285.00; 100µg   $385.00
CASP1 / Caspase 1 Antibody - Anti-CASP1 / Caspase 1 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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Rabbit Polyclonal (IgG) to Human CASP1 / Caspase 1
Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
50µg   0.25mg/ml   $425.00
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Rat Monoclonal [clone 1H11] (IgG1) to Mouse CASP1 / Caspase 1
Mouse
ELISA, Flo, WB
Unconjugated
100µg   $680.00
CASP1 / Caspase 1 Antibody - CASP1 / Caspase 1 antibody. IHC(P): Human Breast Cancer Tissue.
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Rabbit Polyclonal to Human CASP1 / Caspase 1
Human
IHC, IHC-P, WB
Unconjugated
100µg   0.5mg/ml   $355.00
CASP1 / Caspase 1 Antibody - Western blot of Cleaved-Caspase-1 (D210) antibody
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Rabbit Polyclonal (IgG) to Human CASP1 / Caspase 1
Human
ELISA, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
Select
Rabbit Polyclonal to Human CASP1 / Caspase 1
Human
IHC, IP, WB
Unconjugated
200µg   1000µl   0.2mg/ml   $295.00
CASP1 / Caspase 1 Antibody - Western blot of CASP1 expression in transfected 293T cell line by CASP1 monoclonal antibody (M01), clone 3D2.
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Mouse Monoclonal [clone 3D2] (IgG2a,k) to Human CASP1 / Caspase 1
Human
ELISA, WB
Unconjugated
100µg   1mg/ml   $365.00
Select
Rabbit Polyclonal to Human CASP1 / Caspase 1
Mouse, Rat, Human
ICC, IP, WB
Unconjugated
100µg   $635.00
Select
Rabbit Polyclonal (IgG) to Human CASP1 / Caspase 1
Human
ELISA, IHC
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
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Rabbit Polyclonal to Insect CASP1 / Caspase 1
ELISA, WB
Unconjugated
100µg   0.5mg/ml   $325.00
CASP1 / Caspase 1 Antibody - Caspase-1(P20) antibody Western blot. Lane 1: Rat Brain Tissue Lysate. Lane 2: Rat Spleen Tissue Lysate. Lane 3: Mouse Brain Tissue Lysate. Lane 4: Mouse Spleen Tissue Lysate. Lane 5: Mouse Testis Tissue Lysate.
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Rabbit Polyclonal to Mouse CASP1 / Caspase 1
Mouse, Rat
WB
Unconjugated
100µg   0.5mg/ml   $325.00
CASP1 / Caspase 1 Antibody - CASP1 / Caspase 1 antibody. IHC(P): Human Breast Cancer Tissue.
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Rabbit Polyclonal to Human CASP1 / Caspase 1
Human
IHC, IHC-P, WB
Unconjugated
100µg   0.5mg/ml   $355.00
CASP1 / Caspase 1 Antibody - Western blot of recombinant CASP1 / Caspase 1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal to Pig CASP1 / Caspase 1
Pig, Human
ICC, IP, WB
Unconjugated
100µl   0.5mg/ml   $275.00; 200µl   0.5mg/ml   $325.00; 500µl   0.5mg/ml   $485.00; 1ml   0.5mg/ml   $605.00
CASP1 / Caspase 1 Antibody - Formalin-fixed, paraffin-embedded section of human reactive lymph node stained for Caspase-1 expression (antibody) using a DAB chromogen and Hematoxylin counterstain. B is a higher magnification of A. Staining in macrophages is observed.
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Rabbit Polyclonal (IgG) to Human CASP1 / Caspase 1
Human
IHC, IHC-P, WB
Unconjugated
100µg   200µl   0.5mg/ml   $335.00
Select
Rabbit Polyclonal to Human CASP1 / Caspase 1
Mouse, Rat, Human
IHC, WB
Unconjugated
0.1ml   $235.00; 0.5ml   $445.00; 1ml   $710.00
CASP1 / Caspase 1 Antibody - Fig-1: Western blot analysis of Caspase 1. Anti-Caspase 1 antibody was used at 2 µg/ml on A431 lysate.
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Mouse Monoclonal [clone ABM1B93] (IgG1,k) to Human CASP1 / Caspase 1
Mouse, Human
WB
Unconjugated
25µg   $225.00; 100µg   $345.00
CASP1 / Caspase 1 Antibody - 1:100 staining mouse brain tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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Rabbit Polyclonal (IgG) to Human CASP1 / Caspase 1
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
CASP1 / Caspase 1 Antibody - CASP1 / Caspase 1 antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human CASP1 / Caspase 1
Horse, Human
WB
Unconjugated
100µl   0.5mg/ml   $365.00
CASP1 / Caspase 1 Antibody - Staining 293 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
Select
Rabbit Polyclonal (IgG) to Human CASP1 / Caspase 1
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
CASP1 / Caspase 1 Antibody - Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Caspase 1 Antibody. The picture on the right is blocked with the synthesized peptide.
Select
Rabbit Polyclonal (IgG) to Human CASP1 / Caspase 1
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
CASP1 / Caspase 1 Antibody - Immunohistochemistry analysis of paraffin-embedded human brain, using Caspase 1 (Phospho-Ser376) Antibody. The picture on the right is blocked with the phospho peptide.
Select
Rabbit Polyclonal (IgG) to Human CASP1 / Caspase 1
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00

Viewing 1-25 of 124 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).