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CASK
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1.
| Gene Name: | calcium/calmodulin-dependent serine protein kinase (MAGUK family) |
| Family/Subfamily: | Protein Kinase , CASK |
| Synonyms: | CASK, CAMGUK, Cask/lin-2, CMG, FGS4, LIN2, MICPCH, HCASK, Protein Kinase Cask, Protein lin-2 homolog, CAGH39, MRXSNA, TNRC8 |
| Target Sequences: | NM_003688 NP_003679.2 O14936 |
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